Expression of Msgn1 in paraxial mesoderm

Stable Identifier
R-MMU-9794031
Type
Reaction [omitted]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Expression of Msgn1 in paraxial mesoderm
Tbx6 and Lef1:Ctnnb1 bound to the Msgn1 promoter act synergistically to promote transcription of Msgn1 (Wittler et al. 2007, Chalamalasetty et al. 2011, Campbell et al. 2022). Msgn1 is expressed in unsegmented paraxial mesoderm but expression ceases in nascent somites (Yoon et al. 2000).
Literature References
PubMed ID Title Journal Year
21750544 The Wnt3a/β-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program

Chalamalasetty, RB, Yamaguchi, TP, Iacovino, M, Feigenbaum, L, Biris, KK, Dunty, WC, Kyba, M, Yoon, JK, Chapman, DL, Ajima, R, Beisaw, A

Nat Commun 2011
17668009 Expression of Msgn1 in the presomitic mesoderm is controlled by synergism of WNT signalling and Tbx6

Werber, M, Kispert, A, Gossler, A, Grote, P, Beckers, A, Shin, EH, Herrmann, BG, Wittler, L

EMBO Rep 2007
10837126 The bHLH class protein pMesogenin1 can specify paraxial mesoderm phenotypes

Moon, RT, Yoon, JK, Wold, B

Dev Biol 2000
Participants
Input
Output
Orthologous Events
Expression of MSGN1 in paraxial mesoderm (Homo sapiens)
Authored
May, B  (2022-06-24)
Reviewed
Chalamalasetty, RB  (2022-11-09)
Yamaguchi, TP  (2022-11-09)
Created
May, B  (2022-06-27)
Cite Us!