Expression of Ppargc1a (Pgc-1alpha)

Stable Identifier
R-MMU-9717150
Type
Reaction [omitted]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Expression of Ppargc1a (Pgc-1alpha)
The Ppargc1a gene is transcribed to yield mRNA and the mRNA is translated to yield Ppargc1a protein (Puigserver et al. 1998, Handschin et al. 2003).
Literature References
PubMed ID Title Journal Year
9529258 A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

Spiegelman, BM, Park, CW, Wu, Z, Graves, R, Wright, M, Puigserver, P

Cell 1998
12764228 An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle

Spiegelman, BM, Tarr, PT, Handschin, C, Rhee, J, Lin, J

Proc Natl Acad Sci U S A 2003
Participants
Input
Output
This event is regulated
Positively by
Regulator
Mef2c,d:Ppargc1a [nucleoplasm] (Mus musculus)
Orthologous Events
Expression of PPARGC1A (PGC-1alpha) (Homo sapiens)
Authored
May, B  (2021-03-04)
Reviewed
Somers, J  (2021-01-23)
Lezza, AM  (2013-12-07)
Created
May, B  (2021-03-04)
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