p-Y-Stat1,3,5 dimer binds Socs3 gene

Stable Identifier
R-MMU-9705459
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
p-Y-Stat1,3,5 dimer binds Socs3 gene

Stat1 (Auernhammer et al. 1999, Gatto et al. 2004), Stat3 (Auernhammer et al. 1999, Hou et al. 2008), and Stat5 (Emanuelli et al. 2000) dimers bind the 5' region of the Socs3 gene.

Literature References
PubMed ID Title Journal Year
14742442 Analysis of SOCS-3 promoter responses to interferon gamma

Gatto, L, Berlato, C, Poli, V, Tininini, S, Kinjyo, I, Yoshimura, A, Cassatella, MA, Bazzoni, F

J. Biol. Chem. 2004
18782771 The STAT3 NH2-terminal domain stabilizes enhanceosome assembly by interacting with the p300 bromodomain

Hou, T, Ray, S, Lee, C, Brasier, AR

J Biol Chem 2008
10821852 SOCS-3 is an insulin-induced negative regulator of insulin signaling

Emanuelli, B, Peraldi, P, Filloux, C, Sawka-Verhelle, D, Hilton, D, Van Obberghen, E

J Biol Chem 2000
10359822 Autoregulation of pituitary corticotroph SOCS-3 expression: characterization of the murine SOCS-3 promoter

Auernhammer, CJ, Bousquet, C, Melmed, S

Proc Natl Acad Sci U S A 1999
Participants
Orthologous Events
Authored
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