Expression of Fgf9 in testis differentiation

Stable Identifier
R-MMU-9692136
Type
Reaction [omitted]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Expression of Fgf9 in testis differentiation

The Fgf9 gene is transcribed to yield mRNA and the mRNA is translated to yield Fgf9 protein (Kim et al. 2006, Li et al. 2014). In the developing testis, Fgf9 transcription is activated by Sox9 (Li et al. 2014).

Literature References
PubMed ID Title Journal Year
25088423 The sex-determining factors SRY and SOX9 regulate similar target genes and promote testis cord formation during testicular differentiation

Li, Y, Zheng, M, Lau, YF

Cell Rep 2014
16700629 Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination

Kim, Y, Kobayashi, A, Sekido, R, DiNapoli, L, Brennan, J, Chaboissier, MC, Poulat, F, Behringer, RR, Lovell-Badge, R, Capel, B

PLoS Biol. 2006
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