Csf3:Csf3r induces phosphorylation of Jak1

Stable Identifier
R-MMU-9674900
Type
Reaction [omitted]
Species
Mus musculus
Compartment
plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Csf3:Csf3r induces phosphorylation of Jak1
Jak1 is phosphorylated in response to Csf3 binding Csf3r and phosphorylated Jak1 is required for subsequent phosporylation of Csf3r (Shimoda et al 1997).
Literature References
PubMed ID Title Journal Year
9226159 Jak1 plays an essential role for receptor phosphorylation and Stat activation in response to granulocyte colony-stimulating factor

Nagata, S, Ihle, JN, Murakami, H, Stark, GR, Rogers, NC, Feng, J, Shimoda, K, Kerr, IM, Watling, D

Blood 1997
Participants
Input
Output
Orthologous Events
CSF3 dimer:2xCSF3R:LYN:JAK1 induces phosphorylation of JAK1 (Homo sapiens)
Authored
May, B  (2020-01-27)
Reviewed
Touw, IP  (2020-12-12)
Created
May, B  (2020-01-29)
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