p-T-Eif2ak1:2xferriheme dimer [cytosol]

Stable Identifier
R-MMU-9655555
Type
Complex
Species
Mus musculus
Compartment
Literature References
PubMed ID Title Journal Year
16893190 Characterization of heme-regulated eIF2alpha kinase: roles of the N-terminal domain in the oligomeric state, heme binding, catalysis, and inhibition

Shimizu, T, Kurokawa, H, Igarashi, J, Sagami, I, Minami, M, Yamauchi, S, Miksanova, M

Biochemistry 2006
17597215 Identification of Cys385 in the isolated kinase insertion domain of heme-regulated eIF2 alpha kinase (HRI) as the heme axial ligand by site-directed mutagenesis and spectral characterization

Shimizu, T, Kitagawa, T, El-Mashtoly, S, Hirai, K, Igarashi, J, Saiful, I, Martinkova, M, Yamauchi, S

J. Inorg. Biochem. 2007
18450746 Elucidation of the heme binding site of heme-regulated eukaryotic initiation factor 2alpha kinase and the role of the regulatory motif in heme sensing by spectroscopic and catalytic studies of mutant proteins

Shimizu, T, Pichierri, F, Murase, M, Igarashi, J, Martinkova, M, Iizuka, A

J. Biol. Chem. 2008
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