Atf4 and Cebpg bind the Asns gene

Stable Identifier
R-MMU-9644310
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Atf4 and Cebpg bind the Asns gene

Atf4 and Cebpg bind a CEBP-ATF response element (CARE) in the promoter of the Asns gene (Huggins et al. 2015). Eif2ak1 acts via Atf4 to activate transcription of Asns in response to iron deficiency (Zhang et al. 2019).

Literature References
PubMed ID Title Journal Year
26667036 C/EBPγ Is a Critical Regulator of Cellular Stress Response Networks through Heterodimerization with ATF4

Huggins, CJ, Mayekar, MK, Martin, N, Saylor, KL, Gonit, M, Jailwala, P, Kasoji, M, Haines, DC, Quiñones, OA, Johnson, PF

Mol. Cell. Biol. 2015
31033440 HRI coordinates translation necessary for protein homeostasis and mitochondrial function in erythropoiesis

Zhang, S, Macias-Garcia, A, Ulirsch, JC, Velazquez, J, Butty, VL, Levine, SS, Sankaran, VG, Chen, JJ

Elife 2019
Participants
Orthologous Events
Authored
Reviewed
Created