Atf4 and Cebpg bind the Asns gene

Stable Identifier
R-MMU-9644310
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Atf4 and Cebpg bind the Asns gene
Atf4 and Cebpg bind a CEBP-ATF response element (CARE) in the promoter of the Asns gene (Huggins et al. 2015). Eif2ak1 acts via Atf4 to activate transcription of Asns in response to iron deficiency (Zhang et al. 2019).
Literature References
PubMed ID Title Journal Year
31033440 HRI coordinates translation necessary for protein homeostasis and mitochondrial function in erythropoiesis

Macias-Garcia, A, Zhang, S, Butty, VL, Levine, SS, Sankaran, VG, Velazquez, J, Ulirsch, JC, Chen, JJ

Elife 2019
26667036 C/EBPγ Is a Critical Regulator of Cellular Stress Response Networks through Heterodimerization with ATF4

Haines, DC, Jailwala, P, Saylor, KL, Huggins, CJ, Quiñones, OA, Johnson, PF, Martin, N, Kasoji, M, Gonit, M, Mayekar, MK

Mol. Cell. Biol. 2015
Participants
Input
Output
Orthologous Events
ATF4 and CEBPB,CEBPG bind the ASNS gene (Homo sapiens)
Authored
May, B  (2019-04-12)
Reviewed
Staschke, KA  (2019-11-20)
Chen, JJ  (2019-10-22)
Bruhat, A  (2019-09-15)
Created
May, B  (2019-04-12)
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