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Eif2s3x [cytosol]
Stable Identifier
R-MMU-9633494
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
Eukaryotic translation initiation factor 2 subunit 3, X-linked, IF2G_MOUSE
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to mitochondrial stress (Mus musculus)
DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
p-S52-EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
Unfolded Protein Response (UPR) (Mus musculus)
PERK regulates gene expression (Mus musculus)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
p-S52-EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
Metabolism of proteins (Mus musculus)
Translation (Mus musculus)
Eukaryotic Translation Initiation (Mus musculus)
Cap-dependent Translation Initiation (Mus musculus)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Mus musculus)
Translation initiation complex formation (Mus musculus)
Formation of translation initiation complexes containing mRNA that does not circularize (Mus musculus)
43S complex [cytosol] (Mus musculus)
ternary complex [cytosol] (Mus musculus)
eIF2:GTP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
48S complex [cytosol] (Mus musculus)
43S complex [cytosol] (Mus musculus)
ternary complex [cytosol] (Mus musculus)
eIF2:GTP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Mus musculus)
43S complex [cytosol] (Mus musculus)
ternary complex [cytosol] (Mus musculus)
eIF2:GTP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Mus musculus)
43S complex [cytosol] (Mus musculus)
ternary complex [cytosol] (Mus musculus)
eIF2:GTP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
Formation of the ternary complex, and subsequently, the 43S complex (Mus musculus)
De novo formation of eIF2:GTP (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
eIF2:GTP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
Formation of the 43S pre-initiation complex (Mus musculus)
43S complex [cytosol] (Mus musculus)
ternary complex [cytosol] (Mus musculus)
eIF2:GTP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
ternary complex [cytosol] (Mus musculus)
eIF2:GTP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Mus musculus)
eIF2:GTP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
ternary complex [cytosol] (Mus musculus)
eIF2:GTP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
GTP hydrolysis and joining of the 60S ribosomal subunit (Mus musculus)
eIF2:GTP is hydrolyzed, eIFs are released (Mus musculus)
48S complex [cytosol] (Mus musculus)
43S complex [cytosol] (Mus musculus)
ternary complex [cytosol] (Mus musculus)
eIF2:GTP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
eIF2:GDP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
Recycling of eIF2:GDP (Mus musculus)
Formation of eIF2:GDP:eIF2B intermediate (Mus musculus)
eIF2:GDP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
eIF2:GDP: eIF2B [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
eIF2 activation (Mus musculus)
eIF2:GDP: eIF2B [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
eIF2:GTP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
Ribosomal scanning and start codon recognition (Mus musculus)
Ribosomal scanning (Mus musculus)
48S complex [cytosol] (Mus musculus)
43S complex [cytosol] (Mus musculus)
ternary complex [cytosol] (Mus musculus)
eIF2:GTP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
Start codon recognition (Mus musculus)
48S complex [cytosol] (Mus musculus)
43S complex [cytosol] (Mus musculus)
ternary complex [cytosol] (Mus musculus)
eIF2:GTP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
L13a-mediated translational silencing of Ceruloplasmin expression (Mus musculus)
Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Mus musculus)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Mus musculus)
43S complex [cytosol] (Mus musculus)
ternary complex [cytosol] (Mus musculus)
eIF2:GTP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (Mus musculus)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Mus musculus)
43S complex [cytosol] (Mus musculus)
ternary complex [cytosol] (Mus musculus)
eIF2:GTP [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
Transport of small molecules (Mus musculus)
ABC-family proteins mediated transport (Mus musculus)
ABCF1 binds EIF2 (Mus musculus)
ABCF1:EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Eif2s3x [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9Z0N1 Eif2s3x
Gene Names
Eif2s3x
Chain
initiator methionine:, chain:2-472
Reference Genes
BioGPS Gene:26905 Eif2s3x
CTD Gene:26905 Eif2s3x
ENSEMBL:ENSMUSG00000035150.16 Eif2s3x
KEGG Gene (Mus musculus):26905 Eif2s3x
Monarch:26905 Eif2s3x
NCBI Gene:26905 Eif2s3x
UCSC:Q9Z0N1 Eif2s3x
Reference Transcript
RefSeq:NM_012010.3 Eif2s3x
Other Identifiers
10605740
1421895_at
1423744_x_at
1451090_a_at
17543229
26905
4340615
4395112
4478666
4555239
4559756
4585415
4593402
4861969
4994989
5109765
5144886
5200449
5209159
5233197
5261939
5419204
5424038
5473715
5511313
94252_at
A_51_P256154
A_51_P305532
A_52_P314042
A_55_P2093764
A_55_P2624903
GE1538552
GE35348
GO:0000049
GO:0000166
GO:0001731
GO:0002181
GO:0002183
GO:0003723
GO:0003743
GO:0003824
GO:0003924
GO:0005525
GO:0005737
GO:0005829
GO:0005850
GO:0006412
GO:0006413
GO:0008135
GO:0016787
GO:0045182
GO:0045202
GO:0065003
GO:1990856
ILMN_2649129
Msa.10450.0_s_at
aa274159_at
aa274159_g_at
mMC012265
Participates
as a member of
Eif2s3x,y [cytosol] (Mus musculus)
as a component of
p-S52-EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Mus musculus)
Inferred From
EIF2S3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_036140.1
IntEnz
3.6.5.3
Ensembl
ENSMUST00000050328
,
ENSMUSP00000059395
,
ENSMUSG00000035150
PRO
Q9Z0N1
MGI
1349431
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