Neil3 recognizes and binds to spiroiminodihydantoin in telomeric DNA

Stable Identifier
R-MMU-9629370
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Neil3 recognizes and binds to spiroiminodihydantoin in telomeric DNA

Mouse Neil3 recognizes and binds telomeric DNA oligomers containing oxidatively damaged guanine in the form of spiroiminodihydantoin (Sp) (Zhou et al. 2013).

Literature References
PubMed ID Title Journal Year
23926102 Neil3 and NEIL1 DNA glycosylases remove oxidative damages from quadruplex DNA and exhibit preferences for lesions in the telomeric sequence context

Zhou, J, Liu, M, Fleming, AM, Burrows, CJ, Wallace, SS

J. Biol. Chem. 2013
Participants
Orthologous Events
Authored
Reviewed
Created