Neil3 recognizes and binds to spiroiminodihydantoin in telomeric DNA

Stable Identifier
R-MMU-9629370
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Neil3 recognizes and binds to spiroiminodihydantoin in telomeric DNA
Mouse Neil3 recognizes and binds telomeric DNA oligomers containing oxidatively damaged guanine in the form of spiroiminodihydantoin (Sp) (Zhou et al. 2013).
Literature References
PubMed ID Title Journal Year
23926102 Neil3 and NEIL1 DNA glycosylases remove oxidative damages from quadruplex DNA and exhibit preferences for lesions in the telomeric sequence context

Burrows, CJ, Liu, M, Fleming, AM, Wallace, SS, Zhou, J

J. Biol. Chem. 2013
Participants
Input
Output
Orthologous Events
NEIL3 recognizes and binds to spiroiminodihydantoin in telomeric DNA (Homo sapiens)
Authored
Orlic-Milacic, M  (2019-01-05)
Reviewed
Zhou, J  (2019-02-11)
Created
Orlic-Milacic, M  (2018-11-21)
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