Foxo1:Ppargc1a binds G6pc gene promoter

Stable Identifier
R-MMU-9623231
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Foxo1:Ppargc1a binds G6pc gene promoter
The complex of Foxo1 and Pgc-1alpha binds the promoter of the G6pc gene, encoding Glucose-6-phosphatase (Puigserver et al. 2003).
Literature References
PubMed ID Title Journal Year
12754525 Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

Walkey, CJ, Spiegelman, BM, Dong, H, Puigserver, P, Accili, D, Oriente, F, Rhee, J, Altomonte, J, Yoon, JC, Donovan, J, Kitamura, Y

Nature 2003
Participants
Input
Output
This event is regulated
Negatively by
Regulator
Insulin [extracellular region] (Mus musculus)
Orthologous Events
FOXO1,FOXO1:PPARGC1A,FOXO3,FOXO4,FOXO6 bind G6PC gene promoter (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-10-11)
Reviewed
Bertaggia, E  (2018-10-26)
Donlon, T  (2018-10-17)
Created
Orlic-Milacic, M  (2018-10-03)
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