Reactome | phospho-Foxo6 [nucleoplasm]

phospho-Foxo6 [nucleoplasm]

Stable Identifier

R-MMU-9614995

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

p-T26,S184-FOXO6, Q70KY4

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - FOXO-mediated transcription (Mus musculus)
      - Regulation of localization of FOXO transcription factors (Mus musculus)
        
        AKT phosphorylates FOXO transcription factors (Mus musculus)
        
        p-T24,S256,S319-FOXO1,p-T32,S253,S315-FOXO3,p-T32,S197,S262-FOXO4,(p-T26,S184-FOXO6) [nucleoplasm] (Mus musculus)
        
        phospho-Foxo6 [nucleoplasm] (Mus musculus)

Signal Transduction (Mus musculus)

- Intracellular signaling by second messengers (Mus musculus)
  - PIP3 activates AKT signaling (Mus musculus)
    - AKT phosphorylates targets in the nucleus (Mus musculus)
      - AKT phosphorylates FOXO transcription factors (Mus musculus)
        
        p-T24,S256,S319-FOXO1,p-T32,S253,S315-FOXO3,p-T32,S197,S262-FOXO4,(p-T26,S184-FOXO6) [nucleoplasm] (Mus musculus)
        
        phospho-Foxo6 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q70KY4 Foxo6

Gene Names

Foxo6

Chain

chain:1-559

Reference Genes

BioGPS Gene:329934 Foxo6

ENSEMBL:ENSMUSG00000052135.9 Foxo6

KEGG Gene (Mus musculus):329934 Foxo6

Monarch:329934 Foxo6

NCBI Gene:329934 Foxo6

UCSC:Q70KY4 Foxo6

Reference Transcript

RefSeq:NM_194060.1 Foxo6

Other Identifiers

10515939

17429449

329934

4501137

4732242

4746865

4817272

4851009

4855886

4894456

5038732

5125426

5134315

5251023

5508022

A_52_P589568

A_55_P2092226

GE1554989

GO:0000978

GO:0000981

GO:0003677

GO:0003700

GO:0005634

GO:0005654

GO:0005737

GO:0006351

GO:0006355

GO:0006357

GO:0007613

GO:0030154

GO:0043226

GO:0043565

GO:0048856

GO:0050877

GO:0060999

GO:0140110

ILMN_2763092

ILMN_3072147

ILMN_3150922

mMC025645

Participates

as a candidate of

p-T24,S256,S319-FOXO1,p-T32,S253,S315-FOXO3,p-T32,S197,S262-FOXO4,(p-T26,S184-FOXO6) [nucleoplasm] (Mus musculus)

Other forms of this molecule

Foxo6 [nucleoplasm]

Inferred From

p-T26,S184-FOXO6 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 26 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Name

O-phospho-L-serine at 184 (in Homo sapiens)

Coordinate

184

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

NP_918949.1

Ensembl

ENSMUSG00000052135, ENSMUST00000102656, ENSMUSP00000099716

PRO

Q70KY4

MGI

2676586

Cite Us!