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phospho-Notch4 [cytosol]
Stable Identifier
R-MMU-9604329
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
p-4S-NICD4, P31695
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Signaling by NOTCH (Mus musculus)
Signaling by NOTCH4 (Mus musculus)
NOTCH4 Activation and Transmission of Signal to the Nucleus (Mus musculus)
NICD4 traffics to the nucleus (Mus musculus)
p-4S-NICD4:YWHAZ dimer [cytosol] (Mus musculus)
phospho-Notch4 [cytosol] (Mus musculus)
Negative regulation of NOTCH4 signaling (Mus musculus)
AKT1 phosphorylates NOTCH4 (Mus musculus)
phospho-Notch4 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:P31695 Notch4
Gene Names
Notch4, Int-3, Int3
Chain
signal peptide:1-20, chain:21-1964, chain:1411-1964, chain:1428-1964, chain:1463-1964
Reference Genes
BioGPS Gene:18132 Notch4
ENSEMBL:ENSMUSG00000015468.15 Notch4
KEGG Gene (Mus musculus):18132 Notch4
Monarch:18132 Notch4
NCBI Gene:18132 Notch4
UCSC:P31695 Notch4
Reference Transcript
RefSeq:NM_010929.2 Notch4
Other Identifiers
10444352
1449146_at
17336559
18132
4392041
4413184
4423708
4428079
4441132
4473388
4488430
4489373
4495631
4553183
4594535
4601166
4627729
4645368
4671702
4687139
4696089
4747156
4755149
4830102
4860499
4863381
4870820
4904754
5030709
5081806
5100622
5110826
5148772
5167724
5171207
5197851
5202237
5240635
5356645
5373597
5378845
5379538
5444812
5454802
5466565
5472543
5504200
5572574
5604254
92652_at
A_51_P195875
A_55_P2740966
GE35816
GO:0000122
GO:0000987
GO:0001228
GO:0001569
GO:0001763
GO:0001837
GO:0001886
GO:0001944
GO:0003677
GO:0005112
GO:0005509
GO:0005515
GO:0005634
GO:0005654
GO:0005783
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0007155
GO:0007219
GO:0007275
GO:0008593
GO:0009986
GO:0016020
GO:0023052
GO:0030154
GO:0030879
GO:0031410
GO:0032880
GO:0038023
GO:0043226
GO:0045446
GO:0045595
GO:0045602
GO:0045746
GO:0045766
GO:0045944
GO:0048845
GO:0048856
GO:0050793
GO:0051152
GO:0051604
GO:0060089
GO:0060354
GO:0070613
GO:0140110
GO:1903849
GO:2000048
ILMN_1220697
ILMN_1256134
ILMN_2668324
mMC003358
mMC024266
u43691_s_at
Participates
as an output of
AKT1 phosphorylates NOTCH4 (Mus musculus)
as a component of
p-4S-NICD4:YWHAZ dimer [cytosol] (Mus musculus)
Other forms of this molecule
PolyUb-p-NICD4 [nucleoplasm]
p-NICD4 [nucleoplasm]
NICD4 [nucleoplasm]
NICD4 [cytosol]
Notch4(1428-1462) [plasma membrane]
NEXT4 [plasma membrane]
Notch4 Extracellular Domain (NECD4) [plasma membrane]
Notch4 Transmembrane and Intracellular Domain (NTMICD4) [plasma membrane]
Notch4 [cytosol]
Notch4 [nucleoplasm]
Glc,GlcNAc-Fuc-Pre-Notch4 [Golgi membrane]
Notch4 [Golgi membrane]
Notch4 [plasma membrane]
Notch4 [Golgi membrane]
Glc,Fuc-Pre-Notch4 [Golgi membrane]
Glc,Fuc-Pre-Notch4 [endoplasmic reticulum membrane]
Fuc-Pre-Notch4 [endoplasmic reticulum membrane]
Pre-Notch4 [endoplasmic reticulum membrane]
Notch4 [Golgi membrane]
Notch4 [Golgi membrane]
Notch4 [extracellular region]
Notch4 [plasma membrane]
Notch4 [Golgi membrane]
Inferred From
p-4S-NICD4 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 1495 (in Homo sapiens)
Coordinate
1495
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1847 (in Homo sapiens)
Coordinate
1847
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1865 (in Homo sapiens)
Coordinate
1865
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1917 (in Homo sapiens)
Coordinate
1917
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_035059.2
Ensembl
ENSMUSP00000015612
,
ENSMUSG00000015468
,
ENSMUST00000015612
PRO
P31695
MGI
107471
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q93794
1
sel-10 [cytosol]
(R-CEL-5688973)
0.524
2
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