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NLRC5 [cytosol]
Stable Identifier
R-MMU-937324
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
C3VPR6
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Signaling by Interleukins (Mus musculus)
Interleukin-1 family signaling (Mus musculus)
Interleukin-1 signaling (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
NLRC5 binds IKBKB and CHUK (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
Innate Immune System (Mus musculus)
Toll-like Receptor Cascades (Mus musculus)
Toll Like Receptor 10 (TLR10) Cascade (Mus musculus)
MyD88 cascade initiated on plasma membrane (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
NLRC5 binds IKBKB and CHUK (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
Toll Like Receptor 2 (TLR2) Cascade (Mus musculus)
Toll Like Receptor TLR1:TLR2 Cascade (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
NLRC5 binds IKBKB and CHUK (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
Toll Like Receptor TLR6:TLR2 Cascade (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
NLRC5 binds IKBKB and CHUK (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
Toll Like Receptor 3 (TLR3) Cascade (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
NLRC5 binds IKBKB and CHUK (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
Toll Like Receptor 4 (TLR4) Cascade (Mus musculus)
MyD88-independent TLR4 cascade (Mus musculus)
TRIF (TICAM1)-mediated TLR4 signaling (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
NLRC5 binds IKBKB and CHUK (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
NLRC5 binds IKBKB and CHUK (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
Toll Like Receptor 5 (TLR5) Cascade (Mus musculus)
MyD88 cascade initiated on plasma membrane (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
NLRC5 binds IKBKB and CHUK (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Mus musculus)
MyD88 dependent cascade initiated on endosome (Mus musculus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
NLRC5 binds IKBKB and CHUK (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
Toll Like Receptor 9 (TLR9) Cascade (Mus musculus)
MyD88 dependent cascade initiated on endosome (Mus musculus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Regulation of NF-kappa B signaling (Mus musculus)
NLRC5 binds IKBKB and CHUK (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
TRAF2,6 ubiquitinates NLRC5 (Mus musculus)
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
USP14 deubiquitinates NLRC5 (Mus musculus)
NLRC5 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:C3VPR6
Reference Genes
BioGPS Gene:434341
ENSEMBL:ENSMUSG00000074151
ENSEMBL:ENSMUSG00000074151.15
KEGG Gene (Mus musculus):434341
Monarch:434341
NCBI Gene:434341
UCSC:C3VPR6
Reference Transcript
RefSeq:XM_006531163.2
RefSeq:NM_001033207.3
RefSeq:XM_011248428.1
RefSeq:XM_006531162.2
Other Identifiers
10574098
10574100
10574102
10574104
10574133
10574135
10574137
10574139
10574141
10574143
10574145
10574149
10574151
10574153
10574155
10574157
10574159
10574161
10574163
114306_at
1437176_at
17504023
4317033
4328114
4334968
434341
4345704
4359822
4377844
4383072
4402620
4413218
4451941
4460157
4478527
4483983
4537386
4559263
4566628
4571969
4627750
4648449
4698388
4716585
4734844
4759889
4777630
4836958
4917020
4924025
4985564
5001665
5021372
5030996
5066993
5073317
5078476
5080344
5102569
5105235
5123819
5216816
5217744
5228825
5274733
5304836
5321727
5344956
5377060
5402313
5516358
5519135
5520831
5521402
5527872
5542461
5550109
5554694
5587021
A_30_P01023590
A_30_P01023799
A_30_P01028457
A_52_P382107
A_55_P2016034
A_66_P113043
GE1419566
GO:0000166
GO:0000978
GO:0002376
GO:0003677
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0006351
GO:0006355
GO:0009617
GO:0009966
GO:0023052
GO:0032088
GO:0035556
GO:0043226
GO:0045087
GO:0045088
GO:0045345
GO:0045944
GO:0051607
GO:0060335
GO:0060339
GO:0060340
GO:0098542
ILMN_3161790
Participates
as an input of
NLRC5 binds IKBKB and CHUK (Mus musculus)
as an output of
USP14 deubiquitinates NLRC5 (Mus musculus)
as a component of
CHUK:IKBKB:NLRC5 [endoplasmic reticulum membrane] (Mus musculus)
Other forms of this molecule
K63polyUb-NLRC5 [cytosol]
Inferred From
NLRC5 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_011246730.1
,
NP_001028379.2
,
XP_006531225.1
,
XP_006531226.1
Ensembl
ENSMUSG00000074151
,
ENSMUST00000053085
,
ENSMUST00000211816
,
ENSMUSP00000148677
,
ENSMUSP00000138322
PRO
C3VPR6
MGI
3612191
PDB
2MJM
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q60680
3
phospho-p-T23-CHUK [cytosol]
(R-MMU-198615)
phospho-p-S176,S180-CHUK [cytosol]
(R-MMU-177667)
CHUK [cytosol]
(R-MMU-168104)
0.524
4
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