Interaction of MEKK1 with TRAF6

Stable Identifier
R-MMU-933534
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Interaction of MEKK1 with TRAF6

TRAF6 requires MEKK1 (MAP3K1) to activate NF-kB and MEKK1 may interact with TRAF6, which in turn contributes to the activation of IKK and MAPKK, leading to the activation of NF-kB and AP-1. (Yoshida et al)

Literature References
PubMed ID Title Journal Year
18984593 TRAF6 and MEKK1 play a pivotal role in the RIG-I-like helicase antiviral pathway

Yoshida, R, Takaesu, G, Yoshida, H, Okamoto, F, Yoshioka, T, Choi, Y, Akira, S, Kawai, T, Yoshimura, A, Kobayashi, T

J Biol Chem 2008
Participants
Orthologous Events
Authored
Reviewed
Created