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K48-Ub [cytosol]
Stable Identifier
R-MMU-912722
Type
Set [DefinedSet]
Species
Mus musculus
Compartment
cytosol
Synonyms
K48-ubiquitin
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
TCR signaling (Mus musculus)
Downstream TCR signaling (Mus musculus)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Signaling by Interleukins (Mus musculus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Mus musculus)
Regulation of signaling by CBL (Mus musculus)
CBL ubiquitinates PI3K (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
TNFR2 non-canonical NF-kB pathway (Mus musculus)
K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
NIK-->noncanonical NF-kB signaling (Mus musculus)
SCF-beta-TRCP ubiquitinates p-7S-p100:RELB in active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
Innate Immune System (Mus musculus)
C-type lectin receptors (CLRs) (Mus musculus)
CLEC7A (Dectin-1) signaling (Mus musculus)
Dectin-1 mediated noncanonical NF-kB signaling (Mus musculus)
SCF-beta-TRCP ubiquitinates p-7S-p100:RELB in active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
Fc epsilon receptor (FCERI) signaling (Mus musculus)
FCERI mediated NF-kB activation (Mus musculus)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Deubiquitination (Mus musculus)
Josephin domain DUBs (Mus musculus)
ATXN3 deubiquitinates polyUb-PARK2 (Mus musculus)
PolyUb [cytosol] (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
PARK2 autoubiquitinates (Mus musculus)
PolyUb [cytosol] (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
Ovarian tumor domain proteases (Mus musculus)
OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
TNFAIP3 (A20) ubiquitinates RIPK1 (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
Ub-specific processing proteases (Mus musculus)
USP10 deubiquitinates SNX3, CFTR (Mus musculus)
PolyUb [cytosol] (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
USP11 deubiquitinates NFKBIA (Mus musculus)
PolyUb [cytosol] (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Mus musculus)
PolyUb [cytosol] (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
USP18 deubiquitinates TAK1:TAB1 (Mus musculus)
PolyUb [cytosol] (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
USP20, USP33 deubiquitinate ADRB2 (Mus musculus)
PolyUb [cytosol] (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
USP21 deubiquitinates RIPK1,DDX58 (Mus musculus)
PolyUb [cytosol] (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
USP25 deubiquitinates DDX58 (Mus musculus)
PolyUb [cytosol] (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
USP33 deubiquitinates CCP110,ARRB (Mus musculus)
PolyUb [cytosol] (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
USP4 deubiquitinate TRAF2,TRAF6 (Mus musculus)
PolyUb [cytosol] (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
USP5 cleaves polyubiquitin (Mus musculus)
USP5:PolyUb [cytosol] (Mus musculus)
PolyUb [cytosol] (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
USP8 deubiquitinates RNF128 (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
Programmed Cell Death (Mus musculus)
Regulated Necrosis (Mus musculus)
RIPK1-mediated regulated necrosis (Mus musculus)
Regulation of necroptotic cell death (Mus musculus)
BIRC2/3 (cIAP1/2) is autoubiquitinated (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Death Receptor Signalling (Mus musculus)
TNF signaling (Mus musculus)
Regulation of TNFR1 signaling (Mus musculus)
TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
K48polyUb-RIPK1-containing TNFR1 complexes [plasma membrane] (Mus musculus)
K48polyUb [cytosol] (Mus musculus)
K48-Ub [cytosol] (Mus musculus)
Participants
members
Ub-48-RPS27A(1-76) [cytosol] (Mus musculus)
Ub-48-UBA52(1-76) [cytosol] (Mus musculus)
Ub-48-UBB(1-76) [cytosol] (Mus musculus)
Ub-124-UBB(77-152) [cytosol] (Mus musculus)
Ub-200-UBB(153-228) [cytosol] (Mus musculus)
Ub-48-UBC(1-76) [cytosol] (Mus musculus)
Ub-124-UBC(77-152) [cytosol] (Mus musculus)
Ub-200-UBC(153-228) [cytosol] (Mus musculus)
Ub-276-UBC(229-304) [cytosol] (Mus musculus)
Ub-352-UBC(305-380) [cytosol] (Mus musculus)
Ub-428-UBC(381-456) [cytosol] (Mus musculus)
Ub-504-UBC(457-532) [cytosol] (Mus musculus)
Ub-580-UBC(533-608) [cytosol] (Mus musculus)
Ub-656-UBC(609-684) [cytosol] (Mus musculus)
Participant Of
input
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex
SCF-beta-TRCP ubiquitinates p-7S-p100:RELB in active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP
repeatedUnit
K48polyUb [cytosol]
Inferred From
K48-Ub [cytosol] (Homo sapiens)
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