Reactome | Atp6v1d [cytosol]

Atp6v1d [cytosol]

Stable Identifier

R-MMU-912597

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

ATP6V1D, P57746

Locations in the PathwayBrowser

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Cellular responses to external stimuli (Mus musculus)

- Cellular responses to stress (Mus musculus)
  - Amino acids regulate mTORC1 (Mus musculus)
    - RRAGA,B exchanges GDP for GTP (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
    - RRAGA,B hydrolyzes GTP (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
    - RRAGC,D exchanges GTP for GDP (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
    - RRAGC,D hydrolyzes GTP (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
    - mTORC1 binds RHEB:GTP (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
    - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
    - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
    - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)

Signal Transduction (Mus musculus)

- Signaling by Receptor Tyrosine Kinases (Mus musculus)
  - Signaling by Insulin receptor (Mus musculus)
    - Insulin receptor recycling (Mus musculus)
      - ATP6AP1 binds V-ATPase (Mus musculus)
        
        V-ATPase [endosome membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Mus musculus)
        
        V-ATPase [endosome membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)
      - Endosome acidification (Mus musculus)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Mus musculus)
        
        V-ATPase [endosome membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        Atp6v1d [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:P57746

Gene Names

Atp6v1d

Reference Genes

BioGPS Gene:73834 Atp6v1d

ENSEMBL:ENSMUSG00000021114

KEGG Gene (Mus musculus):73834 Atp6v1d

Monarch:73834 Atp6v1d

NCBI Gene:73834 Atp6v1d

UCSC:P57746 Atp6v1d

Reference Transcript

RefSeq:NM_023721.2 Atp6v1d

Other Identifiers

10401138

1416951_a_at

1416952_at

1438993_a_at

17282104

4366520

4475175

4484624

4595086

4654442

4694677

4812310

5110567

5191289

5214713

5297582

5534079

5608135

73834

96951_at

A_51_P393598

GE1490024

GE40494

GO:0003674

GO:0005575

GO:0005622

GO:0005813

GO:0005815

GO:0005856

GO:0005929

GO:0006810

GO:0006811

GO:0008150

GO:0016020

GO:0022607

GO:0022857

GO:0030030

GO:0032991

GO:0033176

GO:0042626

GO:0043226

GO:0046961

GO:0055085

GO:0060271

GO:0061512

GO:1902600

ILMN_2647048

Msa.9511.0_f_at

mMR030491

Participant Of

hasComponent

ATP6V1 [cytosol]

Other forms of this molecule

Atp6v1d [plasma membrane]

Atp6v1d [specific granule membrane]

Inferred From

ATP6V1D [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_076210.1

Ensembl

ENSMUSP00000021536, ENSMUST00000021536, ENSMUSG00000021114

PRO

P57746

MGI

1921084

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