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Structural maintenance of chromosomes protein 3 [nucleoplasm]
Stable Identifier
R-MMU-912387
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
Smc3, SMC3_MOUSE, Smc3
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Telophase/Cytokinesis (Mus musculus)
Cohesin Loading onto Chromatin (Mus musculus)
Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 (Mus musculus)
Cohesin:PDS5:WAPAL [nucleoplasm] (Mus musculus)
Cohesin Complex [nucleoplasm] (Mus musculus)
Structural maintenance of chromosomes protein 3 [nucleoplasm] (Mus musculus)
Cohesin:PDS5:WAPAL:NIPBL:MAU2:Chromatin [nucleoplasm] (Mus musculus)
Cohesin:PDS5:WAPAL:NIPBL:MAU2:Centromere [nucleoplasm] (Mus musculus)
Cohesin:PDS5:WAPAL [nucleoplasm] (Mus musculus)
Cohesin Complex [nucleoplasm] (Mus musculus)
Structural maintenance of chromosomes protein 3 [nucleoplasm] (Mus musculus)
Cohesin:PDS5:WAPAL:NIPBL:MAU2:Chromosomal Arm [nucleoplasm] (Mus musculus)
Cohesin:PDS5:WAPAL [nucleoplasm] (Mus musculus)
Cohesin Complex [nucleoplasm] (Mus musculus)
Structural maintenance of chromosomes protein 3 [nucleoplasm] (Mus musculus)
Cohesin binds PDS5 and WAPAL (Mus musculus)
Cohesin Complex [nucleoplasm] (Mus musculus)
Structural maintenance of chromosomes protein 3 [nucleoplasm] (Mus musculus)
Cohesin:PDS5:WAPAL [nucleoplasm] (Mus musculus)
Cohesin Complex [nucleoplasm] (Mus musculus)
Structural maintenance of chromosomes protein 3 [nucleoplasm] (Mus musculus)
S Phase (Mus musculus)
Establishment of Sister Chromatid Cohesion (Mus musculus)
Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Mus musculus)
Cohesin:PDS5:WAPAL:Centromere [nucleoplasm] (Mus musculus)
Cohesin:PDS5:WAPAL [nucleoplasm] (Mus musculus)
Cohesin Complex [nucleoplasm] (Mus musculus)
Structural maintenance of chromosomes protein 3 [nucleoplasm] (Mus musculus)
Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Mus musculus)
Cohesin:PDS5:WAPAL:Chromosomal Arm [nucleoplasm] (Mus musculus)
Cohesin:PDS5:WAPAL [nucleoplasm] (Mus musculus)
Cohesin Complex [nucleoplasm] (Mus musculus)
Structural maintenance of chromosomes protein 3 [nucleoplasm] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
SUMOylation (Mus musculus)
SUMO E3 ligases SUMOylate target proteins (Mus musculus)
SUMOylation of DNA damage response and repair proteins (Mus musculus)
SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 (Mus musculus)
Cohesin Complex [nucleoplasm] (Mus musculus)
Structural maintenance of chromosomes protein 3 [nucleoplasm] (Mus musculus)
SUMOylated Cohesin [nucleoplasm] (Mus musculus)
Structural maintenance of chromosomes protein 3 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9CW03 Smc3
Gene Names
Smc3, Bam, Bmh, Cspg6, Mmip1, Smc3l1, Smcd
Chain
chain:1-1217
Reference Genes
BioGPS Gene:13006 Smc3
KEGG:mmu:13006 Smc3
Monarch:13006 Smc3
NCBI Gene:13006 Smc3
UCSC:Q9CW03 Smc3
Reference Transcript
RefSeq:NM_007790.3 Smc3
Other Identifiers
102853_at
10463951
13006
1450950_at
1450951_at
17360355
4322018
4327627
4332612
4353195
4385679
4394119
4417602
4419013
4432079
4435893
4470901
4502181
4524778
4535288
4593327
4643859
4679392
4680450
4688371
4785933
4850497
4850925
4853509
4908900
4933704
4936353
4959666
4991395
5006690
5016276
5045435
5065864
5080803
5116205
5139926
5176574
5182748
5184474
5268309
5292062
5350594
5486703
5551750
5582003
5594186
5606993
A_52_P138002
A_55_P2130610
A_66_P111148
GE34906
GO:0000166
GO:0000775
GO:0000785
GO:0000795
GO:0000800
GO:0000987
GO:0003677
GO:0003682
GO:0003690
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005694
GO:0006275
GO:0006281
GO:0006974
GO:0007010
GO:0007062
GO:0007064
GO:0008092
GO:0008278
GO:0016363
GO:0016787
GO:0016887
GO:0019827
GO:0022414
GO:0030892
GO:0030893
GO:0036033
GO:0046982
GO:0048487
GO:0051276
GO:0051301
GO:0051321
GO:0070840
GO:0090307
GO:0097431
ILMN_1223531
ILMN_2602761
ILMN_2604080
ILMN_2678413
aa209705_s_at
mMC006421
mMC021385
mMC022459
mMR001358
Participates
as a component of
SUMOylated Cohesin [nucleoplasm] (Mus musculus)
Meiotic Cohesin complex [nucleoplasm] (Mus musculus)
Cohesin Complex [nucleoplasm] (Mus musculus)
Other forms of this molecule
Smc3 [cytosol]
Smc3 [cytosol]
Smc3 [chromosome]
Smc3 [chromosome, centromeric region]
Smc3 [nucleoplasm]
Inferred From
SMC3 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_031816.2
ENSEMBL
ENSMUST00000025930
,
ENSMUSG00000024974
,
ENSMUSP00000025930
PRO
Q9CW03
GlyGen
Q9CW03
MGI
1339795
PDB
7DG5
,
2WD5
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q7Z5K2 WAPL
4
WAPAL [cytosol]
(R-HSA-2484802)
WAPAL [chromosome]
(R-HSA-2577090)
WAPAL [chromosome, centromeric region]
(R-HSA-2577088)
WAPAL [nucleoplasm]
(R-HSA-2466355)
0.597
4
UniProt:O60216 RAD21
14
RAD21 [nucleoplasm]
(R-HSA-163042)
RAD21 [chromosome, centromeric region]
(R-HSA-2466012)
RAD21 [chromosome]
(R-HSA-1638775)
p-S454-RAD21 [chromosome]
(R-HSA-2485164)
p-S454-RAD21 [cytosol]
(R-HSA-2500310)
p-S454-RAD21 [chromosome, centromeric region]
(R-HSA-2485163)
RAD21(1-172) [chromosome, centromeric region]
(R-HSA-2467793)
p-S454-RAD21(451-631) [chromosome, centromeric region]
(R-HSA-2467790)
RAD21(173-450) [chromosome, centromeric region]
(R-HSA-2500296)
RAD21(1-172) [cytosol]
(R-HSA-2484901)
RAD21(173-450) [cytosol]
(R-HSA-2500308)
p-S454-RAD21(451-631) [cytosol]
(R-HSA-2500309)
RAD21 [cytosol]
(R-HSA-2484795)
monoSUMO1-K-RAD21 [nucleoplasm]
(R-HSA-3108183)
0.597
5
UniProt:Q61550 Rad21
15
Rad21 [nucleoplasm]
(R-MMU-3108183)
Double-strand-break repair protein rad21 homolog [nucleoplasm]
(R-MMU-912350)
Rad21 [cytosol]
(R-MMU-2484795)
phospho-Rad21 [cytosol]
(R-MMU-2500309)
Rad21 [cytosol]
(R-MMU-2500308)
Rad21 [cytosol]
(R-MMU-2484901)
Rad21 [chromosome, centromeric region]
(R-MMU-2500296)
phospho-Rad21 [chromosome, centromeric region]
(R-MMU-2467790)
Rad21 [chromosome, centromeric region]
(R-MMU-2467793)
phospho-Rad21 [chromosome, centromeric region]
(R-MMU-2485163)
phospho-Rad21 [cytosol]
(R-MMU-2500310)
phospho-Rad21 [chromosome]
(R-MMU-2485164)
Rad21 [chromosome]
(R-MMU-1638775)
Rad21 [chromosome, centromeric region]
(R-MMU-2466012)
Rad21 [nucleoplasm]
(R-MMU-163042)
0.564
2
UniProt:Q96FF9 CDCA5
6
p-S21,S75,T159-CDCA5 [cytosol]
(R-HSA-2484804)
p-S21,S75,T159-CDCA5 [chromosome]
(R-HSA-2468266)
p-S21,S75,T159-CDCA5 [chromosome, centromeric region]
(R-HSA-2468269)
CDCA5 [chromosome]
(R-HSA-2468149)
CDCA5 [chromosome, centromeric region]
(R-HSA-2468260)
CDCA5 [nucleoplasm]
(R-HSA-2466357)
0.564
3
UniProt:Q9Z2D6 Mecp2
4
phospho-Mecp2 [nucleoplasm]
(R-MMU-9022331)
phospho-Mecp2 [nucleoplasm]
(R-MMU-9022333)
Mecp2 [nucleoplasm]
(R-MMU-9005573)
Mecp2 [nucleoplasm]
(R-MMU-9005539)
0.499
3
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