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About
What is Reactome ?
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IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane]
Stable Identifier
R-MMU-912308
Type
Complex
Species
Mus musculus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Signaling by Interleukins (Mus musculus)
Interleukin-2 family signaling (Mus musculus)
Interleukin receptor SHC signaling (Mus musculus)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Mus musculus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Phosphorylated SHC recruits GRB2:SOS1 (Mus musculus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Phosphorylated SHC1 recruits GRB2:GAB2 (Mus musculus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Phosphorylated SHC1 recruits SHIP (Mus musculus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Mus musculus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
The SHC1:SHIP1 complex is stabilized by GRB2 (Mus musculus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Mus musculus)
Interleukin receptor SHC signaling (Mus musculus)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Mus musculus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Phosphorylated SHC recruits GRB2:SOS1 (Mus musculus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Phosphorylated SHC1 recruits GRB2:GAB2 (Mus musculus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Phosphorylated SHC1 recruits SHIP (Mus musculus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Mus musculus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
The SHC1:SHIP1 complex is stabilized by GRB2 (Mus musculus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Recruitment of SHC1 is mediated by Y593 of the common beta chain (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
SHP1 and SHP2 bind the common beta chain (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
SHP1 and SHP2 dephosphorylate Y628 of IL3RB (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Tyrosine kinases phosphorylate the receptor (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
Signal Transduction (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK1/MAPK3 signaling (Mus musculus)
RAF/MAP kinase cascade (Mus musculus)
RAS GEFs promote RAS nucleotide exchange (Mus musculus)
RAS GEFs [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Mus musculus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Mus musculus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Mus musculus)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
IL3:IL3RA [plasma membrane]
(Mus musculus)
pY593,Y628-IL3RB:JAK2 [plasma membrane]
(Mus musculus)
Participates
as a component of
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Mus musculus)
Inferred From
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane]
(Homo sapiens)
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