Slc2a3 gene expression is stimulated by Mecp2:Creb1 complex

Stable Identifier
R-MMU-9022185
Type
Reaction [omitted]
Species
Mus musculus
Compartment
nucleoplasm, plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Slc2a3 gene expression is stimulated by Mecp2:Creb1 complex
In mouse primary neurons and the hippocampal neuronal cell line HT22, transcription of the Slc2a3 (Glut3) gene, encoding solute carrier family 2, facilitated glucose transporter member 3, is directly stimulated by the complex of Mecp2 and Creb1 (Chen et al. 2013).
Literature References
PubMed ID Title Journal Year
23493374 Creb1-Mecp2-(m)CpG complex transactivates postnatal murine neuronal glucose transporter isoform 3 expression

Thamotharan, S, Chen, Y, Devaskar, SU, Shin, BC

Endocrinology 2013
Participants
Input
Output
This event is regulated
Positively by
Regulator
Mecp2:Creb1:Slc2a3 gene [nucleoplasm] (Mus musculus)
Active Unit
Mecp2:Creb1 [nucleoplasm]
Orthologous Events
SLC2A3 gene expression is stimulated by MECP2:CREB1 complex (Homo sapiens)
Authored
Orlic-Milacic, M  (2017-10-02)
Reviewed
Krishnaraj, R  (2018-08-07)
Christodoulou, J  (2018-08-07)
Created
Orlic-Milacic, M  (2017-09-21)
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