Reactome | Sst(89-116) [extracellular region]

Sst(89-116) [extracellular region]

Stable Identifier

R-MMU-9021913

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

extracellular region

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Mus musculus)
        
        Somatostatin, cortistatin [extracellular region] (Mus musculus)
        
        Somatostatin [extracellular region] (Mus musculus)
        
        Sst(89-116) [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Mus musculus)
        
        Somatostatin, cortistatin [extracellular region] (Mus musculus)
        
        Somatostatin [extracellular region] (Mus musculus)
        
        Sst(89-116) [extracellular region] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Mus musculus)
        
        Somatostatin, cortistatin [extracellular region] (Mus musculus)
        
        Somatostatin [extracellular region] (Mus musculus)
        
        Sst(89-116) [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Mus musculus)
        
        Somatostatin, cortistatin [extracellular region] (Mus musculus)
        
        Somatostatin [extracellular region] (Mus musculus)
        
        Sst(89-116) [extracellular region] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Mus musculus)
        
        Somatostatin, cortistatin [extracellular region] (Mus musculus)
        
        Somatostatin [extracellular region] (Mus musculus)
        
        Sst(89-116) [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Mus musculus)
        
        Somatostatin, cortistatin [extracellular region] (Mus musculus)
        
        Somatostatin [extracellular region] (Mus musculus)
        
        Sst(89-116) [extracellular region] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Peptide ligand-binding receptors (Mus musculus)
        
        Somatostatin receptors bind somatostatin and cortistatin (Mus musculus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Mus musculus)
        
        Somatostatin, cortistatin [extracellular region] (Mus musculus)
        
        Somatostatin [extracellular region] (Mus musculus)
        
        Sst(89-116) [extracellular region] (Mus musculus)
        
        Somatostatin, cortistatin [extracellular region] (Mus musculus)
        
        Somatostatin [extracellular region] (Mus musculus)
        
        Sst(89-116) [extracellular region] (Mus musculus)

External Reference Information

External Reference

UniProt:P60041 Sst

Gene Names

Sst, Smst

Chain

signal peptide:1-24, peptide:25-34, peptide:31-43, propeptide:35-88, peptide:89-116, peptide:103-116

Reference Genes

BioGPS Gene:20604 Sst

ENSEMBL:ENSMUSG00000004366.5 Sst

KEGG Gene (Mus musculus):20604 Sst

Monarch:20604 Sst

NCBI Gene:20604 Sst

UCSC:P60041 Sst

Reference Transcript

RefSeq:NM_009215.1 Sst

Other Identifiers

10438730

1417954_at

17329423

20604

4445229

4626318

4951277

5334932

95436_at

A_51_P262489

A_55_P2837304

GE33690

GO:0005179

GO:0005576

GO:0005615

GO:0006972

GO:0007165

GO:0009410

GO:0010243

GO:0010447

GO:0023052

GO:0030334

GO:0031410

GO:0038170

GO:0042802

GO:0043025

GO:0043200

GO:0043226

GO:0048018

GO:0048545

GO:0048870

GO:0098772

GO:0098982

GO:0098992

GO:0099072

ILMN_2729826

Msa.2612.0_f_at

X51468_f_at

mMC001134

Participates

as a member of

Somatostatin [extracellular region] (Mus musculus)

Other forms of this molecule

Sst(103-116) [extracellular region]

Inferred From

SST(89-116) [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_033241.1

Ensembl

ENSMUST00000004480, ENSMUSG00000004366, ENSMUSP00000004480

PRO

P60041

MGI

98326

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