Mecp2 binds Crh gene promoter

Stable Identifier
R-MMU-9017986
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Mecp2 binds Crh gene promoter

Endogenous mouse Mecp2 binds to the promoter of the endogenous mouse Crh gene, encoding corticotropin-release hormone (corticoliberin) (McGill et al. 2006, Samaco et al. 2012).

Literature References
PubMed ID Title Journal Year
17108082 Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome

Carson, JP, Bundle, SF, Zoghbi, HY, McGill, BE, Yaylaoglu, MB, Thaller, C

Proc. Natl. Acad. Sci. U.S.A. 2006
22231481 Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome

Mandel-Brehm, C, Samaco, RC, Zoghbi, HY, McGill, BE, Shaw, CA, McGraw, CM

Nat. Genet. 2012
Participants
Orthologous Events
Authored
Reviewed
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