Translation of Robo3.2 mRNA is negatively regulated by NMD

Stable Identifier
R-MMU-9014678
Type
Reaction [omitted]
Species
Mus musculus
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Translation of Robo3.2 mRNA is negatively regulated by NMD
In mouse commissural axons, translation of Robo3.2 transcripts at the floor plate is negatively regulated by nonsense mediated decay (NMD) (Colak et al. 2013).
Literature References
PubMed ID Title Journal Year
23746841 Regulation of axon guidance by compartmentalized nonsense-mediated mRNA decay

Jaffrey, SR, Ji, SJ, Porse, BT, Colak, D

Cell 2013
Participants
Input
Output
This event is regulated
Negatively by
Regulator
Robo3.2 mRNA:Upf2:Upf1 [cytosol] (Mus musculus)
Active Unit
Upf2 [cytosol]
Upf1 [cytosol]
Orthologous Events
Translation of ROBO3.2 mRNA is negatively regulated by NMD (Homo sapiens)
Authored
Orlic-Milacic, M  (2017-06-23)
Reviewed
Jaworski, A  (2017-07-31)
Created
Orlic-Milacic, M  (2017-08-02)
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