Robo3 mRNA translation is positively regulated by Msi1

Stable Identifier
R-MMU-9011345
Type
Reaction [omitted]
Species
Mus musculus
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Robo3 mRNA translation is positively regulated by Msi1
Binding of mouse Msi1 to mouse Robo3.1 and Robo3.2 mRNAs positively regulates Robo3.1 and Robo3.2 mRNA translation, resulting in increased protein levels of Robo3.1 and Robo3.2 (Kuwako et al. 2010).
Literature References
PubMed ID Title Journal Year
20696379 Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression

Kuwako, K, Kakumoto, K, Imai, T, Igarashi, M, Hamakubo, T, Sakakibara, S, Tessier-Lavigne, M, Okano, HJ, Okano, H

Neuron 2010
Participants
Input
Output
This event is regulated
Positively by
Regulator
Robo3 mRNA:Msi1 [cytosol] (Mus musculus)
Active Unit
Msi1 [cytosol]
Orthologous Events
ROBO3.1 mRNA translation is positively regulated by MSI1 (Homo sapiens)
Authored
Orlic-Milacic, M  (2017-06-23)
Reviewed
Jaworski, A  (2017-07-31)
Created
Orlic-Milacic, M  (2017-06-30)
Cite Us!