Slit2 gene expression is stimulated by Isl1

Stable Identifier
R-MMU-9010544
Type
Reaction [omitted]
Species
Mus musculus
Compartment
nucleoplasm, plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Slit2 gene expression is stimulated by Isl1
In mice, the transcription factor Isl1, in complex with either Lhx3 or Lhx4, directly stimulates transcription of the Slit2 gene (Kim et al. 2016).
Literature References
PubMed ID Title Journal Year
27819291 ISL1-based LIM complexes control Slit2 transcription in developing cranial motor neurons

Mastick, GS, Kim, HK, Park, C, Park, HC, Kim, N, Gruner, HN, Gergics, P, Lee, H, Song, MR, Kim, KT

Sci Rep 2016
Participants
Input
Output
This event is regulated
Positively by
Regulator
Isl1:Lhx3/4:Ldb1:Slit2 gene [nucleoplasm] (Mus musculus)
Active Unit
Isl1:Lhx3/4:Ldb1 [nucleoplasm]
Orthologous Events
SLIT2 gene expression is stimulated by ISL1 (Homo sapiens)
Authored
Orlic-Milacic, M  (2017-06-23)
Reviewed
Jaworski, A  (2017-07-31)
Created
Orlic-Milacic, M  (2017-06-27)
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