Reactome | Msx2 binds Runx2 gene promoter

Msx2 binds Runx2 gene promoter

Stable Identifier

R-MMU-9007762

Type

Reaction [binding]

Species

Mus musculus

Compartment

nucleoplasm

ReviewStatus

5/5

General

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Mouse Msx2, a homeobox transcription factor, binds to Dlx5 sites in the distal (P1) promoter of the mouse Runx2 gene, thus antagonizing Dlx5 binding (Lee et al. 2005).

Literature References

PubMed ID	Title	Journal	Year
16115867	Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter Choi, KY, Lee, MH, Cho, JY, Wozney, JM, Hwang, YS, Kim, YJ, Choi, JY, Bae, SC, Ryoo, HM, Chi, XZ, Kim, BG, Kim, JI, Yoon, WJ	J. Biol. Chem.	2005