Active Prkaca and CaMK IV phosphorylate Mecp2 at T308

Stable Identifier
R-MMU-9005848
Type
Reaction [transition]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Active Prkaca and CaMK IV phosphorylate Mecp2 at T308

Recombinant mouse Prkaca (PKA C-alpha), as well as the activated recombinant mouse Camk4 complex (CaMK IV), phosphorylate recombinant mouse Mecp2 on threonine residue T308 (Ebert et al. 2013).

Literature References
PubMed ID Title Journal Year
23770587 Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR

Kastan, NR, Greenberg, ME, Ekiert, R, Bird, AP, Lyst, MJ, Hu, LS, Gabel, HW, Cohen, S, Navarro, AJ, Ebert, DH, Robinson, ND

Nature 2013
Participants
Catalyst Activity

calcium-dependent protein kinase activity of Active Prkaca,CaMKIV [nucleoplasm]

Orthologous Events
Authored
Reviewed
Created
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