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Il15 [extracellular region]
Stable Identifier
R-MMU-8983179
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Signaling by Interleukins (Mus musculus)
Interleukin-2 family signaling (Mus musculus)
Interleukin-15 signaling (Mus musculus)
IL15 binds IL15RA (Mus musculus)
IL15:IL15RA [plasma membrane] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
IL15 binds IL2RB:JAK1 and IL2RG:JAK3 (Mus musculus)
IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
IL15:IL15RA binds IL2RB:JAK1 and IL2RG:JAK3 (Mus musculus)
IL15:IL15RA [plasma membrane] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Mus musculus)
IL15:IL15RA [plasma membrane] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
IL15:IL15RA:IL2RB:JAK1:IL2RG:JAK3 translocates from the plasma membrane to the endosome (Mus musculus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Mus musculus)
IL15:IL15RA [plasma membrane] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] (Mus musculus)
IL15:IL15RA [plasma membrane] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:STAT3,STAT5,(STAT3:STAT5) [plasma membrane] (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] (Mus musculus)
IL15:IL15RA [plasma membrane] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:STAT3,STAT5,(STAT3:STAT5) [plasma membrane] (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] (Mus musculus)
IL15:IL15RA [plasma membrane] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-STAT3,p-STAT5,(p-Y-STAT3:p-STAT5) [plasma membrane] (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] (Mus musculus)
IL15:IL15RA [plasma membrane] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 [plasma membrane] (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1 [plasma membrane] (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] (Mus musculus)
IL15:IL15RA [plasma membrane] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2:SOS [plasma membrane] (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 [plasma membrane] (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1 [plasma membrane] (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] (Mus musculus)
IL15:IL15RA [plasma membrane] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Mus musculus)
IL15:IL15RA:IL2RB:p-Y-JAK1:IL2RG:p-JAK3 [plasma membrane] (Mus musculus)
IL15:IL15RA [plasma membrane] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Mus musculus)
IL15:IL15RA [plasma membrane] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
p-Y-STAT3 and p-STAT5 dissociates from IL15:IL15RA:IL2RB:p-JAK1:IL2RG:p-JAK3:p-Y-STAT3:p-STAT5 (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] (Mus musculus)
IL15:IL15RA [plasma membrane] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-STAT3,p-STAT5,(p-Y-STAT3:p-STAT5) [plasma membrane] (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 [plasma membrane] (Mus musculus)
IL15:IL15RA [plasma membrane] (Mus musculus)
Il15 [extracellular region] (Mus musculus)
External Reference Information
External Reference
UniProt:P48346 Il15
Gene Names
Il15
Chain
signal peptide:1-29, propeptide:30-48, chain:49-162
Reference Genes
BioGPS Gene:16168 Il15
ENSEMBL:ENSMUSG00000031712.11 Il15
KEGG Gene (Mus musculus):16168 Il15
Monarch:16168 Il15
NCBI Gene:16168 Il15
UCSC:P48346 Il15
Reference Transcript
RefSeq:XM_006530711.3 Il15
RefSeq:XM_006530706.3 Il15
RefSeq:XM_006530712.3 Il15
RefSeq:XM_006530707.3 Il15
RefSeq:XM_006530713.3 Il15
RefSeq:XM_011248312.2 Il15
RefSeq:NM_001254747.1 Il15
RefSeq:XM_006530708.3 Il15
RefSeq:XM_006530709.2 Il15
RefSeq:XM_011248313.2 Il15
RefSeq:NM_008357.2 Il15
RefSeq:XM_011248314.2 Il15
RefSeq:XM_006530705.3 Il15
RefSeq:XM_006530710.2 Il15
Other Identifiers
10579958
1418219_at
161037_at
16168
17510856
4401603
4403930
4533630
4589562
4614494
4616884
4739610
4832235
4991006
4998563
5130753
5175957
5183567
5340121
5399311
5536511
5539577
5584690
A_52_P15461
A_55_P2744693
A_66_P133150
GE34636
GO:0001779
GO:0001787
GO:0001819
GO:0001866
GO:0002376
GO:0005125
GO:0005126
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006486
GO:0006955
GO:0007155
GO:0008284
GO:0009986
GO:0016192
GO:0016607
GO:0023052
GO:0030154
GO:0030212
GO:0030225
GO:0032740
GO:0032819
GO:0032825
GO:0035723
GO:0036211
GO:0042102
GO:0042119
GO:0042531
GO:0043226
GO:0045062
GO:0045580
GO:0048018
GO:0048469
GO:0048535
GO:0048662
GO:0048856
GO:0050691
GO:0050731
GO:0050766
GO:0050778
GO:0050896
GO:0098542
GO:0098772
GO:0120163
GO:1901135
GO:1904100
ILMN_1219869
ILMN_2610234
ILMN_2938704
U14332_s_at
mMC009424
Participates
as a component of
Il15:Il15ra:p-Y-Il2rb:p-Y-Il2rg:p-Y-Jak1:p-Y-Jak3 [plasma membrane] (Mus musculus)
IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Mus musculus)
Il15:Il15ra:p-Y-Il2rb:p-Y-Il2rg:p-Y-Jak1:p-Y-Jak3 [plasma membrane] (Mus musculus)
Il15:Il15ra:Il2rb:Il2rg:p-Y-Jak1:p-Y-Jak3 [plasma membrane] (Mus musculus)
IL15:IL15RA [plasma membrane] (Mus musculus)
as an input of
IL15 binds IL2RB:JAK1 and IL2RG:JAK3 (Mus musculus)
IL15 binds IL15RA (Mus musculus)
Other forms of this molecule
Il15 [endosome]
Inferred From
IL15 [extracellular region]
(Homo sapiens)
Cross References
RefSeq
NP_032383.1
,
XP_006530774.1
,
XP_006530769.1
,
XP_006530773.1
,
XP_011246616.1
,
XP_011246615.1
,
XP_006530770.1
,
XP_011246614.1
,
XP_006530772.1
,
XP_006530771.1
,
NP_001241676.1
,
XP_006530775.1
,
XP_006530768.1
,
XP_006530776.1
Ensembl
ENSMUST00000034148
,
ENSMUSP00000147848
,
ENSMUSG00000031712
,
ENSMUSP00000034148
,
ENSMUST00000209363
,
ENSMUST00000209573
,
ENSMUSP00000148256
PRO
P48346
MGI
103014
PDB
2PSM
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