The complex of Hdac1, Rbl1 and E2f4 or Hdac1, Rbl2 and E2f4 or E2f5 binds Ccna2 gene promoter

Stable Identifier
R-MMU-8978970
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
The complex of Hdac1, Rbl1 and E2f4 or Hdac1, Rbl2 and E2f4 or E2f5 binds Ccna2 gene promoter

Experiments performed on mouse fibroblasts, including both NIH-3T3 cell line and embryonic fibroblasts, have shown that in G0 and early G1 phase p130 (Rbl2) and p107 (Rbl1) form a complex with the histone deacetylase Hdac1 on the promoter of the Ccna2 gene (Rayman et al. 2002).

Literature References
PubMed ID Title Journal Year
11959842 E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex

Rayman, JB, Takahashi, Y, Indjeian, VB, Dannenberg, JH, Catchpole, S, Watson, RJ, te Riele, H, Dynlacht, BD

Genes Dev 2002
Participants
Orthologous Events
Authored
Reviewed
Created
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