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Commd8 [cytosol]
Stable Identifier
R-MMU-8955107
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
COMMD8, Q9CZG3
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Neddylation (Mus musculus)
26S proteasome degrades HIFalpha (Mus musculus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Mus musculus)
NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Mus musculus)
CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Mus musculus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Mus musculus)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Mus musculus)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Mus musculus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Mus musculus)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Mus musculus)
CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Mus musculus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex (Mus musculus)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Mus musculus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex (Mus musculus)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Mus musculus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Mus musculus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 (Mus musculus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:UBXN7 [cytosol] (Mus musculus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha (Mus musculus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Mus musculus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:UBXN7 [cytosol] (Mus musculus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:hydroxyPro-HIF-alpha [cytosol] (Mus musculus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Mus musculus)
COMMDs:CCDC22 [cytosol] (Mus musculus)
COMMDs [cytosol] (Mus musculus)
Commd8 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9CZG3
Gene Names
Commd8
Reference Genes
BioGPS Gene:27784 Commd8
ENSEMBL:ENSMUSG00000029213
ENSEMBL:ENSMUSG00000029213.12 Commd8
KEGG Gene (Mus musculus):27784 Commd8
Monarch:27784 Commd8
NCBI Gene:27784 Commd8
UCSC:Q9CZG3 Commd8
Reference Transcript
RefSeq:NM_178599.4 Commd8
Other Identifiers
10530434
110702_at
113612_at
1430129_a_at
1455671_at
17448607
27784
4442612
4513251
4600512
4711548
4749723
4813220
4819380
4969751
5015257
5044544
5063289
5204196
A_51_P294340
A_52_P112721
A_55_P2114044
A_55_P2728038
GE1425574
GE39344
GO:0003674
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0008150
GO:0043226
ILMN_2674548
mMC018311
Participates
as a candidate of
COMMDs [cytosol] (Mus musculus)
Other forms of this molecule
Commd8 [nucleoplasm]
Inferred From
COMMD8 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_848714.1
Ensembl
ENSMUST00000013693
,
ENSMUSP00000013693
,
ENSMUSG00000029213
PRO
Q9CZG3
MGI
1343485
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