Runx2:Cbfb and Sp7 bind the Ucma gene promoter

Stable Identifier
R-MMU-8939880
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
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PNG
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 | PPTX  | SBGN
Runx2:Cbfb and Sp7 bind the Ucma gene promoter
In mouse cells, Runx2, presumably associated with Cbfb, and Sp7 (Osx) bind to adjacent Runx2 and Osx binding sites, respectively, in the promoter of the Ucma gene. The Runx2 and Osx binding sites in the Ucma promoter are evolutionarily conserved (Lee et al. 2015).
Literature References
PubMed ID Title Journal Year
25865393 Ucma, a direct transcriptional target of Runx2 and Osterix, promotes osteoblast differentiation and nodule formation

Lee, SJ, Park, SY, Kim, JE, Boo, YC, Lee, YJ, Choi, JY

Osteoarthr. Cartil. 2015
Participants
Input
Output
Orthologous Events
RUNX2 and SP7 bind the UCMA gene promoter (Homo sapiens)
Authored
Orlic-Milacic, M  (2016-09-21)
Reviewed
Ducy, P  (2017-08-04)
Created
Orlic-Milacic, M  (2016-09-21)
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