Reactome | SYT11 [clathrin-coated endocytic vesicle membrane]

SYT11 [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-MMU-8869115

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

Q9R0N3

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Mus musculus)

- Membrane Trafficking (Mus musculus)
  - Clathrin-mediated endocytosis (Mus musculus)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 dimer [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 dimer [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 dimer [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 dimer [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
    - Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Mus musculus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 dimer [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 dimer [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 dimer [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Mus musculus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 dimer [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 dimer [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
    - RAB5 and GAPVD1 bind AP-2 (Mus musculus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 dimer [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        SYT11 [clathrin-coated endocytic vesicle membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9R0N3

Reference Genes

BioGPS Gene:229521

ENSEMBL:ENSMUSG00000068923

ENSEMBL:ENSMUSG00000068923.15

KEGG Gene (Mus musculus):229521

Monarch:229521

NCBI Gene:229521

UCSC:Q9R0N3

Reference Transcript

Other Identifiers

10499431

112781_at

1429314_at

1429315_at

1449264_at

1455176_a_at

1456464_x_at

165460_at

168346_r_at

17406831

229521

4370051

4497065

4630582

4838169

4871440

5104722

5262121

5303228

5538280

98339_at

A_51_P260730

A_55_P1956267

A_55_P2179448

A_55_P2927621

A_66_P107381

GE42764

GO:0000149

GO:0001778

GO:0001786

GO:0001818

GO:0001891

GO:0002376

GO:0005509

GO:0005515

GO:0005544

GO:0005737

GO:0005764

GO:0005765

GO:0005768

GO:0005773

GO:0005794

GO:0005802

GO:0005886

GO:0006906

GO:0006914

GO:0006954

GO:0007612

GO:0007613

GO:0008092

GO:0008289

GO:0009611

GO:0014059

GO:0014069

GO:0016020

GO:0016192

GO:0017158

GO:0023052

GO:0030276

GO:0030424

GO:0030425

GO:0030659

GO:0030665

GO:0030672

GO:0031369

GO:0031410

GO:0031625

GO:0031982

GO:0032009

GO:0032715

GO:0032720

GO:0033602

GO:0042060

GO:0042802

GO:0042995

GO:0043005

GO:0043195

GO:0043197

GO:0043204

GO:0043226

GO:0044297

GO:0045202

GO:0045335

GO:0045806

GO:0046872

GO:0048471

GO:0048487

GO:0048787

GO:0048791

GO:0050765

GO:0050877

GO:0051650

GO:0055037

GO:0055038

GO:0060076

GO:0060077

GO:0061024

GO:0065003

GO:0070382

GO:0071277

GO:0098542

GO:0098685

GO:0098691

GO:0098793

GO:0098794

GO:1900186

GO:1900242

GO:1900243

GO:1900424

GO:1903979

GO:1905154

GO:1905162

GO:1905171

GO:1905444

GO:1990927

ILMN_1233402

ILMN_3063644

ILMN_3141334

Msa.3551.0_s_at

mMC011007

Participates

as a component of

SYT11 dimer [clathrin-coated endocytic vesicle membrane] (Mus musculus)

Other forms of this molecule

SYT11 [plasma membrane]

Inferred From

SYT11 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Cross References

RefSeq

XP_006501411.1, NP_061274.2

Ensembl

ENSMUST00000107505, ENSMUSP00000103129, ENSMUST00000090945, ENSMUSG00000068923, ENSMUSP00000088464

PRO

Q9R0N3

MGI

1859547

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9JI51	2	Vti1a [trans-Golgi network membrane] (R-RNO-6813927) Vti1a [Golgi membrane] (R-RNO-6811035)	0.499	2

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