Reactome | Avpr2 [clathrin-coated endocytic vesicle membrane]

Avpr2 [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-MMU-8869077

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

AVPR2, O88721

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Mus musculus)

- Membrane Trafficking (Mus musculus)
  - Clathrin-mediated endocytosis (Mus musculus)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Avpr2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Avpr2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Avpr2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Avpr2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
    - Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Mus musculus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Avpr2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Avpr2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Avpr2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Mus musculus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Avpr2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Avpr2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
    - RAB5 and GAPVD1 bind AP-2 (Mus musculus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Mus musculus)
        
        Avpr2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:O88721

Gene Names

Avpr2

Reference Genes

BioGPS Gene:12000 Avpr2

ENSEMBL:ENSMUSG00000031390

KEGG:mmu:12000 Avpr2

Monarch:12000 Avpr2

NCBI Gene:12000 Avpr2

UCSC:O88721 Avpr2

Reference Transcript

Other Identifiers

10600310

12000

1450277_at

17535712

4398769

4648487

4729200

4760087

4921436

4940468

5045973

5108361

5231248

5284981

96585_at

A_51_P306933

A_55_P1994462

GE37349

GO:0001992

GO:0003013

GO:0003014

GO:0003084

GO:0004930

GO:0005000

GO:0005768

GO:0005886

GO:0007186

GO:0008284

GO:0008285

GO:0010628

GO:0016020

GO:0021537

GO:0030139

GO:0031410

GO:0032870

GO:0034097

GO:0035811

GO:0038023

GO:0042277

GO:0043226

GO:0045777

GO:0045907

GO:0048471

GO:0048856

GO:0050886

GO:0060089

GO:1902533

ILMN_1252433

ILMN_2604189

mMC021674

Participates

as a component of

AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Mus musculus)

Other forms of this molecule

phospho-Avpr2 [plasma membrane]

Avpr2 [plasma membrane]

Inferred From

AVPR2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Cross References

RefSeq

XP_006527819.1, NP_062277.1

ENSEMBL

ENSMUST00000033765, ENSMUSP00000033765, ENSMUSG00000031390

PRO

O88721

GlyGen

O88721

MGI

88123

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