Cd99 binds Cd99l2

Stable Identifier
R-MMU-8867186
Type
Reaction [binding]
Species
Mus musculus
Compartment
plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Cd99 binds Cd99l2
CD99 is a glycoprotein found on the leukocytes surface. It has been variously described as a human thymus leukemia Ag (Levy et al. 1979), a Ewing's sarcoma-specific membrane marker molecule (Hamilton et al. 1988) and a putative adhesion molecule (termed E2) involved in spontaneous rosette formation of T cells with erythrocytes (Aubrit et al. 1989, Bernard et al. 1988). CD99L2 is a paralog of CD99 that directly interacts with CD99 to form a heterodimer via its cytoplasmic domain. This interaction positively regulates CD99L2 trafficking to cell surfaces (Nam et al. 2013).
Literature References
PubMed ID Title Journal Year
24133166 Interaction of CD99 with its paralog CD99L2 positively regulates CD99L2 trafficking to cell surfaces

Araki, K, Araki, M, Choi, EY, Lee, HY, Lee, IS, Nam, G, Lee, YK, Lee, S, Ma, MJ

J. Immunol. 2013
Participants
Input
Output
Orthologous Events
CD99 binds CD99L2 (Homo sapiens)
Authored
Garapati, P V  (2016-02-19)
Reviewed
Meldal, BH  (2016-09-14)
Created
Garapati, P V  (2016-04-06)
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