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Dab2 [cytosol]
Stable Identifier
R-MMU-8862456
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
DAB2, P98078
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Mus musculus)
Membrane Trafficking (Mus musculus)
Clathrin-mediated endocytosis (Mus musculus)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
BAR domain proteins recruit dynamin (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
Cargo recognition for clathrin-mediated endocytosis (Mus musculus)
DAB2 binds LRP2 (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LDLR is bound by DAB2 and ARH (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
Clathrin recruits PIK3C2A (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
Clathrin recruits auxilins to the clathrin-coated vesicle (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Mus musculus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
Endophilins recruit synaptojanins to the clathrin-coated pit (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
F- and N- BAR domain proteins bind the clathrin-coated pit (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Mus musculus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
RAB5 and GAPVD1 bind AP-2 (Mus musculus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
LRP2:DAB2 [plasma membrane] (Mus musculus)
Dab2 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:P98078
Gene Names
Dab2
Reference Genes
BioGPS Gene:13132 Dab2
ENSEMBL:ENSMUSG00000022150
KEGG Gene (Mus musculus):13132 Dab2
Monarch:13132 Dab2
NCBI Gene:13132 Dab2
UCSC:P98078 Dab2
Reference Transcript
RefSeq:XM_011245324.1 Dab2
RefSeq:NM_001037905.3 Dab2
RefSeq:XM_017316424.1 Dab2
RefSeq:NM_023118.5 Dab2
RefSeq:NM_001008702.2 Dab2
Participates
as a member of
DAB2,LDLRAP1 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
DAB2,LDLRAP1 [plasma membrane] (Mus musculus)
as a component of
LRP2:DAB2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
LRP2:DAB2 [plasma membrane] (Mus musculus)
as an input of
DAB2 binds LRP2 (Mus musculus)
Other forms of this molecule
Dab2 [lysosomal membrane]
Dab2 [plasma membrane]
Inferred From
DAB2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001008702.1
,
XP_017171913.1
,
NP_075607.2
,
XP_011243626.1
,
NP_001032994.1
PRO
P98078
MGI
109175
HMDB Protein
HMDBP14539
PDB
1M7E
,
1P3R
Interactors (11)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96B97 SH3KBP1
3
SH3KBP1 [plasma membrane]
(R-HSA-182955)
SH3KBP1 [cytosol]
(R-HSA-182957)
Ub-SH3KBP1 [cytosol]
(R-HSA-182926)
0.669
9
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.662
4
UniProt:O35625 Axin1
8
Phospho Axin1 [cytosol]
(R-MMU-206175)
Axin1 [cytosol]
(R-MMU-4641133)
phospho-Axin1 [cytosol]
(R-MMU-3640864)
phospho-Axin1 [cytosol]
(R-MMU-3640841)
Axin1 [cytosol]
(R-MMU-205727)
Phospho (3 sites) Axin1 [cytosol]
(R-MMU-205737)
phospho-Axin1 [cytosol]
(R-MMU-206040)
Axin1 [cytosol]
(R-MMU-195249)
0.656
4
UniProt:Q9UM54 MYO6
3
MYO6 [plasma membrane]
(R-HSA-3006691)
MYO6 [lysosomal membrane]
(R-HSA-3006694)
MYO6 [cytosol]
(R-HSA-3006692)
0.632
4
UniProt:Q0JRZ9 FCHO2
1
FCHO2 [cytosol]
(R-HSA-8862260)
0.623
4
UniProt:Q60631 Grb2
3
Grb2 [cytosol]
(R-MMU-74686)
Grb2 [plasma membrane]
(R-MMU-202993)
Grb2 [cytosol]
(R-MMU-443287)
0.576
4
UniProt:P35917
1
FLT4 [plasma membrane]
(R-MMU-195359)
0.558
3
UniProt:Q8C5D8 Pias2
1
PIAS2-1 [nucleoplasm]
(R-MMU-2993785)
0.508
2
UniProt:Q6WKZ7
2
Nostrin [endocytic vesicle membrane]
(R-MMU-535014)
Nostrin [plasma membrane]
(R-MMU-202134)
0.508
2
UniProt:O94973 AP2A2
6
AP2A2(1-939) [endolysosome membrane]
(R-HSA-6784819)
AP2A2(1-939) [ficolin-1-rich granule membrane]
(R-HSA-6800414)
AP2A2(1-939) [secretory granule membrane]
(R-HSA-6800412)
AP2A2(1-939) [clathrin-coated endocytic vesicle membrane]
(R-HSA-5138448)
AP2A2(1-939) [cytosol]
(R-HSA-182155)
AP2A2(1-939) [plasma membrane]
(R-HSA-177502)
0.499
2
UniProt:Q99NH2-1 PARD3
0.499
2
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