Reactome | H2-K1 [ER to Golgi transport vesicle membrane]

H2-K1 [ER to Golgi transport vesicle membrane]

Stable Identifier

R-MMU-8855892-10

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

ER to Golgi transport vesicle membrane

Synonyms

HLA-H, P01901

Locations in the PathwayBrowser

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Immune System (Mus musculus)

- Adaptive Immune System (Mus musculus)
  - Class I MHC mediated antigen processing & presentation (Mus musculus)
    - Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Mus musculus)
      - Budding of COPII coated vesicle (Mus musculus)
        
        COPII vesicle with MHC class I [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Antigen peptide bound class I MHC [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Homologues of HLA-H [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        H2-K1 [ER to Golgi transport vesicle membrane] (Mus musculus)
      - Disassembly of COPII coated vesicle (Mus musculus)
        
        Antigen peptide bound class I MHC [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Homologues of HLA-H [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        H2-K1 [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII vesicle with MHC class I [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Antigen peptide bound class I MHC [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Homologues of HLA-H [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        H2-K1 [ER to Golgi transport vesicle membrane] (Mus musculus)
      - Journey of cargo through Golgi complex (Mus musculus)
        
        Antigen peptide bound class I MHC [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        Homologues of HLA-H [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        H2-K1 [ER to Golgi transport vesicle membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P01901 H2-K1

Gene Names

H2-K1, H2-K

Chain

signal peptide:1-21, chain:22-369

Reference Genes

BioGPS Gene:14972 H2-K1

CTD Gene:14972 H2-K1

ENSEMBL:ENSMUSG00000061232 H2-K1

KEGG Gene (Mus musculus):14972 H2-K1

Monarch:14972 H2-K1

NCBI Gene:14972 H2-K1

UCSC:P01901 H2-K1

Reference Transcript

RefSeq:NM_001001892.2 H2-K1

Other Identifiers

10450075

1425336_x_at

1427746_x_at

14972

17343710

4308599

4375868

4396393

4406155

4454519

4481024

4564929

4610126

4802234

4817797

4849511

4904496

4925583

5321284

5419991

5455231

5487245

5512713

5546478

93120_f_at

97540_f_at

A_51_P198434

A_52_P50496

A_55_P2049647

GO:0002376

GO:0006955

GO:0008150

GO:0019882

ILMN_2588139

ILMN_2732816

mMR026882

u47329_f_at

Participates

as a member of

Homologues of HLA-H [ER to Golgi transport vesicle membrane] (Mus musculus)

Other forms of this molecule

H2-K1 [Golgi membrane]

H2-K1 [ER to Golgi transport vesicle membrane]

H-2 class I histocompatibility antigen, K-B alpha chain [integral component of lumenal side of endoplasmic reticulum membrane]

H2-K1 [early endosome membrane]

H2-K1 [recycling endosome membrane]

H-2 class I histocompatibility antigen, K-B alpha chain [phagocytic vesicle membrane]

H2-K1 [plasma membrane]

H2-K1 [phagocytic vesicle membrane]

H2-K1 [integral component of lumenal side of endoplasmic reticulum membrane]

H2-K1 [plasma membrane]

H2-K1 [azurophil granule membrane]

Inferred From

HLA-H [ER to Golgi transport vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_001001892.2

Ensembl

ENSMUST00000025181, ENSMUSP00000025181, ENSMUSG00000061232

PRO

P01901

MGI

95904

PDB

3TID, 1FZO, 1LEK, 1FZM, 3P4M, 4HS3, 1BQH, 1P4L, 1OSZ, 1NAN, 1KBG, 1LEG, 1LK2, 3PAB, 2FO4, 2OL3, 1FZJ, 2CKB, 1N59, 3C8K, 5OQF, 1P1Z, 4PG9, 1G7Q, 1KPV, 2QRT, 1WBZ, 5OQG, 1S7T, 1VAD, 1S7S, 3TIE, 4PGC, 1KPU, 2VAB, 4PGE, 1VAC, 1S7R, 3P4N, 6GB6, 3RGV, 5OQI, 3CVH, 2VAA, 3ROO, 1T0N, 1RJZ, 2QRI, 1S7Q, 4PV8, 1RK1, 1T0M, 3ROL, 1RJY, 3P9M, 1G6R, 1FO0, 4PV9, 6JQ2, 1MWA, 1RK0, 3P9L, 1NAM, 6JQ3, 2MHA, 1FZK, 4HKJ, 2CLZ, 1KJ3, 2ZSW, 2CLV, 1KJ2, 2ZSV, 1G7P, 4PGB, 3P4O, 2QRS, 4PGD, 5OQH

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P16879 Fes	1	Fes [cytosol] (R-MMU-421078)	0.463	3