Reactome | Haus7 [cytosol]

Haus7 [cytosol]

Stable Identifier

R-MMU-8855200

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

HAUS7, Q8BKT8

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Mus musculus)

- Cilium Assembly (Mus musculus)
  - Anchoring of the basal body to the plasma membrane (Mus musculus)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus7 [cytosol] (Mus musculus)
      - mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus7 [cytosol] (Mus musculus)
    - C2CD3 binds the mother centriole (Mus musculus)
      - mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus7 [cytosol] (Mus musculus)
      - mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus7 [cytosol] (Mus musculus)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Mus musculus)
      - basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus7 [cytosol] (Mus musculus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
        
        basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus7 [cytosol] (Mus musculus)
    - CP110 and CEP97 dissociate from the centriole (Mus musculus)
      - basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus7 [cytosol] (Mus musculus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus7 [cytosol] (Mus musculus)
    - MARK4 binds ODF2 in the centriole (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus7 [cytosol] (Mus musculus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus7 [cytosol] (Mus musculus)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Mus musculus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
        
        basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus7 [cytosol] (Mus musculus)
    - Recruitment of transition zone proteins (Mus musculus)
      - basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus7 [cytosol] (Mus musculus)
      - basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus7 [cytosol] (Mus musculus)
    - The distal appendage proteins recruit TTBK2 (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus7 [cytosol] (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus7 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q8BKT8

Gene Names

Haus7

Reference Genes

BioGPS Gene:73738 Haus7

ENSEMBL:ENSMUSG00000031371

ENSEMBL:ENSMUSG00000031371.15 Haus7

KEGG Gene (Mus musculus):73738 Haus7

Monarch:73738 Haus7

NCBI Gene:73738 Haus7

UCSC:Q8BKT8 Haus7

Reference Transcript

Other Identifiers

10605055

107110_at

1424277_at

17542349

4392432

4436039

4525483

4618283

4720823

4756096

4774495

4780963

5193685

5270569

5451032

5617038

73738

A_51_P438514

A_55_P2083093

GE124360

GO:0003674

GO:0005634

GO:0005730

GO:0005737

GO:0005813

GO:0005815

GO:0005819

GO:0005856

GO:0005874

GO:0005886

GO:0007010

GO:0007049

GO:0007059

GO:0007098

GO:0008092

GO:0031996

GO:0043226

GO:0051011

GO:0051225

GO:0051301

GO:0070652

GO:1990498

ILMN_2641828

mMC010441

Participates

as a component of

HAUS complex [cytosol] (Mus musculus)

Inferred From

HAUS7 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_082909.1, NP_996987.1

Ensembl

ENSMUSG00000031371, ENSMUST00000033737, ENSMUSP00000076479, ENSMUSP00000033737, ENSMUST00000077243

PRO

Q8BKT8

MGI

1920988

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