Reactome | Haus5 [cytosol]

Haus5 [cytosol]

Stable Identifier

R-MMU-8855197

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

HAUS5, Q9D786

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Mus musculus)

- Cilium Assembly (Mus musculus)
  - Anchoring of the basal body to the plasma membrane (Mus musculus)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus5 [cytosol] (Mus musculus)
      - mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus5 [cytosol] (Mus musculus)
    - C2CD3 binds the mother centriole (Mus musculus)
      - mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus5 [cytosol] (Mus musculus)
      - mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus5 [cytosol] (Mus musculus)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Mus musculus)
      - basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus5 [cytosol] (Mus musculus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
        
        basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus5 [cytosol] (Mus musculus)
    - CP110 and CEP97 dissociate from the centriole (Mus musculus)
      - basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus5 [cytosol] (Mus musculus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus5 [cytosol] (Mus musculus)
    - MARK4 binds ODF2 in the centriole (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus5 [cytosol] (Mus musculus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus5 [cytosol] (Mus musculus)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Mus musculus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
        
        basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus5 [cytosol] (Mus musculus)
    - Recruitment of transition zone proteins (Mus musculus)
      - basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus5 [cytosol] (Mus musculus)
      - basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus5 [cytosol] (Mus musculus)
    - The distal appendage proteins recruit TTBK2 (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus5 [cytosol] (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus5 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9D786

Gene Names

Haus5

Reference Genes

BioGPS Gene:71909 Haus5

ENSEMBL:ENSMUSG00000078762

ENSEMBL:ENSMUSG00000078762.11 Haus5

KEGG Gene (Mus musculus):71909 Haus5

Monarch:71909 Haus5

NCBI Gene:71909 Haus5

UCSC:Q9D786 Haus5

Reference Transcript

RefSeq:NM_027999.1 Haus5

Other Identifiers

10352356

10562084

1452715_at

17489251

4317062

4356701

4372926

4378866

4432925

4467228

4511717

4519708

4519796

4529369

4550842

4733480

4803345

4901556

4904328

4971438

5028003

5067814

5243452

5293882

5324362

5343914

5353415

5370035

5388477

5453963

5476277

5495979

5513170

71909

97371_at

A_51_P124008

A_52_P316545

A_55_P1973178

C78757_rc_at

GE39370

GO:0003674

GO:0005737

GO:0005813

GO:0005815

GO:0005819

GO:0005856

GO:0005874

GO:0007010

GO:0007049

GO:0007059

GO:0007098

GO:0043226

GO:0051225

GO:0051301

GO:0070652

GO:1990498

ILMN_1235574

ILMN_1242680

Participates

as a component of

HAUS complex [cytosol] (Mus musculus)

Inferred From

HAUS5 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_082275.1

Ensembl

ENSMUST00000132862, ENSMUSG00000078762, ENSMUSP00000121739, ENSMUSP00000019697, ENSMUST00000019697

PRO

Q9D786

MGI

1919159

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