Reactome | Csf2rb [plasma membrane]

Csf2rb [plasma membrane]

Stable Identifier

R-MMU-879960

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

CSF2RB, P26955

Locations in the PathwayBrowser

Expand all

Immune System (Mus musculus)

- Cytokine Signaling in Immune system (Mus musculus)
  - Signaling by Interleukins (Mus musculus)
    - Interleukin-3, Interleukin-5 and GM-CSF signaling (Mus musculus)
      - Activation of STAT5a/b by JAK2 (Mus musculus)
        
        High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] (Mus musculus)
        
        High affinity GM-CSF receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Mus musculus)
        
        High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Mus musculus)
        
        GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Mus musculus)
        
        High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Mus musculus)
        
        IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        IL3:IL3R active complex, activated JAK2:p-STAT5 [plasma membrane] (Mus musculus)
        
        IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity binding complex dimers of cytokine receptors using Bc. activated JAK2:STAT5 [plasma membrane] (Mus musculus)
        
        High affinity GM-CSF receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Mus musculus)
        
        High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Mus musculus)
        
        GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity IL-5 receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Mus musculus)
        
        High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Mus musculus)
        
        IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        IL3:IL3R active complex, activated JAK2:STAT5 [plasma membrane] (Mus musculus)
        
        IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
      - IL3RB is phosphorylated on Ser-585 (Mus musculus)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Mus musculus)
        
        High affinity GM-CSF receptor complex dimer, inactive JAK2 [plasma membrane] (Mus musculus)
        
        GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Mus musculus)
        
        IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Mus musculus)
        
        IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
      - Interleukin-5:Interleukin-5 receptor alpha binds IL3RB:JAK2 (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
      - JAK2 is phosphorylated, activated (Mus musculus)
        
        High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Mus musculus)
        
        High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Mus musculus)
        
        GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Mus musculus)
        
        IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Mus musculus)
        
        High affinity GM-CSF receptor complex dimer, inactive JAK2 [plasma membrane] (Mus musculus)
        
        GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Mus musculus)
        
        IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Mus musculus)
        
        IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
      - STAT5 is recruited by JAK2 (Mus musculus)
        
        High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Mus musculus)
        
        High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Mus musculus)
        
        GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Mus musculus)
        
        IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity binding complex dimers of cytokine receptors using Bc. activated JAK2:STAT5 [plasma membrane] (Mus musculus)
        
        High affinity GM-CSF receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Mus musculus)
        
        High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Mus musculus)
        
        GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity IL-5 receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Mus musculus)
        
        High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Mus musculus)
        
        IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        IL3:IL3R active complex, activated JAK2:STAT5 [plasma membrane] (Mus musculus)
        
        IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
      - The receptor is activated (Mus musculus)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Mus musculus)
        
        High affinity GM-CSF receptor complex dimer, inactive JAK2 [plasma membrane] (Mus musculus)
        
        GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Mus musculus)
        
        IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Mus musculus)
        
        IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity binding complexes of interleukin receptors using the Common beta chain [plasma membrane] (Mus musculus)
        
        GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
      - Tyrosine kinases phosphorylate the receptor (Mus musculus)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Mus musculus)
        
        High affinity GM-CSF receptor complex dimer, inactive JAK2 [plasma membrane] (Mus musculus)
        
        GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity IL-3 receptor complex dimer, inactive JAK2 [plasma membrane] (Mus musculus)
        
        IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Mus musculus)
        
        IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        Tyrosine kinases that phosphorylate the Common beta chain [plasma membrane] (Mus musculus)
        
        GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        IL3:IL3RA:IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
      - p-STAT5 dissociates from the receptor complex (Mus musculus)
        
        High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Mus musculus)
        
        High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Mus musculus)
        
        GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Mus musculus)
        
        IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] (Mus musculus)
        
        High affinity GM-CSF receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Mus musculus)
        
        High affinity GM-CSF receptor complex dimer, activated JAK2 [plasma membrane] (Mus musculus)
        
        GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:p-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Mus musculus)
        
        High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Mus musculus)
        
        IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)
        
        IL3:IL3R active complex, activated JAK2:p-STAT5 [plasma membrane] (Mus musculus)
        
        IL3:IL3R active complex, p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        IL3:IL3RA:IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        IL3RB:p-Y1007-JAK2 [plasma membrane] (Mus musculus)
        
        Csf2rb [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P26955

Gene Names

Csf2rb

Reference Genes

BioGPS Gene:12983 Csf2rb

ENSEMBL:ENSMUSG00000071713

KEGG:mmu:12983 Csf2rb

Monarch:12983 Csf2rb

NCBI Gene:12983 Csf2rb

UCSC:P26955 Csf2rb

Reference Transcript

Other Identifiers

10425066

113724_at

12983

1421326_at

1450200_s_at

1455660_at

17312716

4308808

4324771

4378973

4389266

4464598

4464600

4482567

4487281

4493771

4494719

4497226

4503244

4547867

4567276

4592844

4632001

4684570

4689531

4712873

4773093

4831412

4855000

4864767

4871558

4957642

4961376

4968346

5016866

5069941

5077816

5079645

5135104

5196732

5245737

5406392

5435164

5477602

5498471

5502959

5535122

5548000

5586395

5590239

5603927

94747_at

94748_g_at

A_52_P492939

A_52_P52618

A_52_P664853

A_55_P2733965

A_55_P2743485

A_66_P123635

GE34899

GO:0001558

GO:0002376

GO:0004896

GO:0005515

GO:0007259

GO:0009897

GO:0016020

GO:0016064

GO:0019221

GO:0038043

GO:0038156

GO:0038157

GO:0070665

ILMN_1236070

ILMN_1253312

ILMN_2688262

M34397_s_at

mMC019766

mMC020347

mMR029215

Participates

as a component of

Other forms of this molecule

phospho-Csf2rb [plasma membrane]

Inferred From

CSF2RB [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_031806.3, XP_006520450.1, NP_001345783.1

ENSEMBL

ENSMUSP00000094082, ENSMUST00000096355, ENSMUST00000230264, ENSMUSG00000071713, ENSMUSP00000154836

PRO

P26955

GlyGen

P26955

MGI

1339759

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