Reactome | Ifna4 [extracellular region]

Ifna4 [extracellular region]

Stable Identifier

R-MMU-877349-7

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

extracellular region

Synonyms

IFNA2, P07351

Locations in the PathwayBrowser

Expand all

Immune System (Mus musculus)

- Cytokine Signaling in Immune system (Mus musculus)
  - Interferon Signaling (Mus musculus)
    - Interferon alpha/beta signaling (Mus musculus)
      - Activation of JAK kinases (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
        
        p-TYK2:p-IFNAR1:SOCS-1/SOCS-3:IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
      - Formation of p-STAT1 homodimer (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
      - IFN alpha/beta binds to IFNAR2 (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
      - Phosphorylation of INFAR1 by TYK2 (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
      - Phosphorylation of STAT2 (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
      - Recruitment of IFNAR1 (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
      - Recruitment of STAT2 to p-IFNAR1 (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
      - Regulation of IFNA/IFNB signaling (Mus musculus)
        
        Dephosphorylation of JAK1 by SHP1 (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
        
        Dephosphorylation of STAT1 by SHP2 (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:STAT1 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
        
        Dephosphorylation of TYK2 by PTP1B (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
      - Release of p-STAT2:p-STAT1 dimer (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifna4 [extracellular region] (Mus musculus)

External Reference Information

External Reference

UniProt:P07351

Gene Names

Ifna4

Reference Genes

BioGPS Gene:15967 Ifna4

ENSEMBL:ENSMUSG00000070904

ENSEMBL:ENSMUSG00000070904.5 Ifna4

KEGG Gene (Mus musculus):15967 Ifna4

Monarch:15967 Ifna4

NCBI Gene:15967 Ifna4

UCSC:P07351 Ifna4

Reference Transcript

RefSeq:NM_010504.2 Ifna4

Other Identifiers

101789_i_at

101790_f_at

10505890

1422408_at

15967

17415369

4983925

5388495

5426068

5431881

5527778

A_51_P355829

GE118948

GO:0002250

GO:0002286

GO:0002323

GO:0002376

GO:0005125

GO:0005126

GO:0005132

GO:0005576

GO:0005615

GO:0006952

GO:0006959

GO:0007165

GO:0019221

GO:0023052

GO:0030154

GO:0030183

GO:0033141

GO:0036211

GO:0042100

GO:0043330

GO:0048018

GO:0048856

GO:0051607

GO:0098542

GO:0098772

ILMN_2738901

Msa.2373.0_f_at

mMC019238

Participates

as a member of

Homologues of IFNA2 [extracellular region] (Mus musculus)

Other forms of this molecule

Ifna4 [extracellular region]

Inferred From

IFNA2 [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_034634.1

Ensembl

ENSMUSP00000092581, ENSMUSG00000070904, ENSMUST00000094973

PRO

P07351

MGI

107664

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