Reactome | Ifnab [extracellular region]

Ifnab [extracellular region]

Stable Identifier

R-MMU-877349

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

extracellular region

Synonyms

IFNA2, L7MTU6

Locations in the PathwayBrowser

Expand all

Immune System (Mus musculus)

- Cytokine Signaling in Immune system (Mus musculus)
  - Interferon Signaling (Mus musculus)
    - Interferon alpha/beta signaling (Mus musculus)
      - Activation of JAK kinases (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
        
        p-TYK2:p-IFNAR1:SOCS-1/SOCS-3:IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
      - Formation of p-STAT1 homodimer (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
      - IFN alpha/beta binds to IFNAR2 (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
      - Phosphorylation of INFAR1 by TYK2 (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
      - Phosphorylation of STAT2 (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
      - Recruitment of IFNAR1 (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
      - Recruitment of STAT2 to p-IFNAR1 (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
      - Regulation of IFNA/IFNB signaling (Mus musculus)
        
        Dephosphorylation of JAK1 by SHP1 (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
        
        Dephosphorylation of STAT1 by SHP2 (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:STAT1 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
        
        Dephosphorylation of TYK2 by PTP1B (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
      - Release of p-STAT2:p-STAT1 dimer (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Mus musculus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Mus musculus)
        
        IFNA [extracellular region] (Mus musculus)
        
        Homologues of IFNA2 [extracellular region] (Mus musculus)
        
        Ifnab [extracellular region] (Mus musculus)

External Reference Information

External Reference

UniProt:L7MTU6

Gene Names

Ifnab

Reference Genes

BioGPS Gene:15974 Ifnab

CTD Gene:15974 Ifnab

ENSEMBL:ENSMUSG00000100079

ENSEMBL:ENSMUSG00000100079.2 Ifnab

KEGG Gene (Mus musculus):15974 Ifnab

Monarch:15974 Ifnab

NCBI Gene:15974 Ifnab

UCSC:L7MTU6 Ifnab

Reference Transcript

RefSeq:NM_008336.2 Ifnab

Other Identifiers

101317_f_at

10514317

1450613_x_at

15974

17427104

4334235

4388290

4536548

4983925

5038196

5064794

5191743

5204390

5260048

5397851

5426068

5585809

A_55_P2030076

A_55_P2030077

GE117980

GO:0002250

GO:0002286

GO:0002323

GO:0002376

GO:0005125

GO:0005126

GO:0005132

GO:0005576

GO:0005615

GO:0006952

GO:0006959

GO:0019221

GO:0023052

GO:0030154

GO:0030183

GO:0033141

GO:0036211

GO:0042100

GO:0043330

GO:0048018

GO:0048856

GO:0051607

GO:0098542

GO:0098772

ILMN_1223579

ILMN_2770778

Msa.1383.0_at

mMC025495

Participates

as a member of

Homologues of IFNA2 [extracellular region] (Mus musculus)

Other forms of this molecule

Ifnab [extracellular region]

Inferred From

IFNA2 [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_032362.2

Ensembl

ENSMUSP00000071333, ENSMUSG00000100079, ENSMUST00000071378

MGI

1097683

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