Reactome | Rprd1a [nucleoplasm]

Rprd1a [nucleoplasm]

Stable Identifier

R-MMU-6814899

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

RPRD1A, Q8VDS4

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - RNA polymerase II transcribes snRNA genes (Mus musculus)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Mus musculus)
        
        RPRD1A,B [nucleoplasm] (Mus musculus)
        
        Rprd1a [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Mus musculus)
        
        RPRD1A,B [nucleoplasm] (Mus musculus)
        
        Rprd1a [nucleoplasm] (Mus musculus)
    - Integrator complex processes the 3' end of snRNA (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Mus musculus)
        
        RPRD1A,B [nucleoplasm] (Mus musculus)
        
        Rprd1a [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Mus musculus)
        
        RPRD1A,B [nucleoplasm] (Mus musculus)
        
        Rprd1a [nucleoplasm] (Mus musculus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Mus musculus)
        
        RPRD1A,B [nucleoplasm] (Mus musculus)
        
        Rprd1a [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Mus musculus)
        
        RPRD1A,B [nucleoplasm] (Mus musculus)
        
        Rprd1a [nucleoplasm] (Mus musculus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Mus musculus)
        
        RPRD1A,B [nucleoplasm] (Mus musculus)
        
        Rprd1a [nucleoplasm] (Mus musculus)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RPRD1A,B:RPRD2:RPAP2 [nucleoplasm] (Mus musculus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Mus musculus)
        
        RPRD1A,B [nucleoplasm] (Mus musculus)
        
        Rprd1a [nucleoplasm] (Mus musculus)
    - RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Mus musculus)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RPRD1A,B:RPRD2:RPAP2 [nucleoplasm] (Mus musculus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Mus musculus)
        
        RPRD1A,B [nucleoplasm] (Mus musculus)
        
        Rprd1a [nucleoplasm] (Mus musculus)
      - RPRD1A,B:RPRD1A,B [nucleoplasm] (Mus musculus)
        
        RPRD1A,B [nucleoplasm] (Mus musculus)
        
        Rprd1a [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q8VDS4

Gene Names

Rprd1a

Reference Genes

BioGPS Gene:225283 Rprd1a

ENSEMBL:ENSMUSG00000040446

ENSEMBL:ENSMUSG00000040446.5 Rprd1a

KEGG Gene (Mus musculus):225283 Rprd1a

Monarch:225283 Rprd1a

NCBI Gene:225283 Rprd1a

UCSC:Q8VDS4 Rprd1a

Reference Transcript

Other Identifiers

10457862

1451631_at

1454964_at

160782_at

17353143

225283

4328939

4345571

4432303

4466185

4476632

4571012

4690698

4808684

4829451

4841499

4863732

4866390

4964808

5017506

5035803

5099060

5215330

5225476

5243126

5291602

5309897

5316233

5386110

5390926

5410471

5479640

5486964

5597649

A_51_P375406

A_51_P400944

A_51_P472159

GE1540451

GO:0000993

GO:0001111

GO:0005634

GO:0006351

GO:0016071

GO:0031124

GO:0042802

GO:0043226

GO:0097550

GO:0099122

ILMN_1239180

ILMN_2776876

aa547624_at

mMC022844

mMR030054

Participates

as a member of

RPRD1A,B [nucleoplasm] (Mus musculus)

Inferred From

RPRD1A [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_659110.1, XP_006525888.1, XP_006525887.1

Ensembl

ENSMUSG00000040446, ENSMUSP00000043618, ENSMUST00000046206

PRO

Q8VDS4

MGI

2385066

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