Gdpd5 hydrolyzes GPCho

Stable Identifier
R-MMU-6814137
Type
Reaction [transition]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Gdpd5 hydrolyzes GPCho

Mouse enzyme Gdpd5 (Glycerophosphodiester phosphodiesterase domain-containing protein 5; Gde2) catalyzes the hydrolysis of GPCho (glycero-3-phosphocholine) to G3P (glycerol-3-phosphate) and Cho (choline). The protein co-localizes with endoplasmic reticulum marker proteins (Gallazzini et al. 2008).

Literature References
PubMed ID Title Journal Year
18667693 GDPD5 is a glycerophosphocholine phosphodiesterase that osmotically regulates the osmoprotective organic osmolyte GPC

Ferraris, JD, Burg, MB, Gallazzini, M

Proc. Natl. Acad. Sci. U.S.A. 2008
Participants
Catalyst Activity

glycerophosphocholine phosphodiesterase activity of Gdpd5 [endoplasmic reticulum membrane]

Orthologous Events
Authored
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