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Pten [nucleoplasm]
Stable Identifier
R-MMU-6807273
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
PTEN, O08586
Locations in the PathwayBrowser for interactor UniProt:Q9JHL1 NHRF2
Expand all
Signal Transduction (Mus musculus)
Intracellular signaling by second messengers (Mus musculus)
PIP3 activates AKT signaling (Mus musculus)
PTEN Regulation (Mus musculus)
Regulation of PTEN localization (Mus musculus)
Deubiquitinated PTEN translocates to the cytosol (Mus musculus)
Pten [nucleoplasm] (Mus musculus)
USP7 deubiquitinates monoubiquitinated PTEN (Mus musculus)
Pten [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:O08586
Gene Names
Pten
Reference Genes
BioGPS Gene:19211 Pten
ENSEMBL:ENSMUSG00000013663
ENSEMBL:ENSMUSG00000013663.9 Pten
KEGG Gene (Mus musculus):19211 Pten
Monarch:19211 Pten
NCBI Gene:19211 Pten
UCSC:O08586 Pten
Reference Transcript
RefSeq:NM_008960.2 Pten
Other Identifiers
10462521
108490_at
1422553_at
1450655_at
1454722_at
1455728_at
160614_at
163933_at
17358706
17548973
19211
4331488
4380980
4426406
4474971
4536150
4574828
4731500
4815017
4823291
4823758
4844321
4901615
4901848
4927792
4974777
5034273
5039746
5044319
5152414
5225813
5330932
5353743
5391557
5393719
5437453
5471135
5495803
5549728
94989_at
A_51_P275350
A_52_P121155
A_52_P24843
A_55_P2631679
GE42554
GO:0000278
GO:0001525
GO:0001933
GO:0002376
GO:0002902
GO:0003824
GO:0004438
GO:0004721
GO:0004722
GO:0004725
GO:0005161
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005886
GO:0006470
GO:0006629
GO:0006915
GO:0007010
GO:0007056
GO:0007059
GO:0007155
GO:0007270
GO:0007399
GO:0007416
GO:0007417
GO:0007507
GO:0007611
GO:0007613
GO:0007626
GO:0008283
GO:0008284
GO:0008285
GO:0009898
GO:0010467
GO:0010628
GO:0010666
GO:0010719
GO:0010975
GO:0010977
GO:0010997
GO:0012501
GO:0014069
GO:0016192
GO:0016311
GO:0016314
GO:0016324
GO:0016477
GO:0016605
GO:0016787
GO:0016791
GO:0017018
GO:0019899
GO:0019901
GO:0021542
GO:0021955
GO:0022414
GO:0023052
GO:0030154
GO:0030163
GO:0030165
GO:0030336
GO:0030351
GO:0030534
GO:0030889
GO:0031175
GO:0031642
GO:0031647
GO:0032228
GO:0032286
GO:0032535
GO:0032755
GO:0032760
GO:0032869
GO:0033137
GO:0033555
GO:0034330
GO:0035176
GO:0035255
GO:0035749
GO:0036211
GO:0036294
GO:0042060
GO:0042098
GO:0042100
GO:0042130
GO:0042254
GO:0042552
GO:0042711
GO:0042802
GO:0042995
GO:0043005
GO:0043065
GO:0043066
GO:0043197
GO:0043220
GO:0043226
GO:0043491
GO:0043542
GO:0044320
GO:0045202
GO:0045211
GO:0045475
GO:0045666
GO:0045786
GO:0045792
GO:0046621
GO:0046856
GO:0048008
GO:0048679
GO:0048681
GO:0048738
GO:0048853
GO:0048854
GO:0048856
GO:0048870
GO:0050680
GO:0050771
GO:0050821
GO:0050877
GO:0051179
GO:0051548
GO:0051717
GO:0051726
GO:0051800
GO:0051895
GO:0051896
GO:0051898
GO:0052866
GO:0060024
GO:0060044
GO:0060070
GO:0060074
GO:0060134
GO:0060179
GO:0060291
GO:0060292
GO:0060341
GO:0060736
GO:0060997
GO:0061002
GO:0061024
GO:0070374
GO:0071257
GO:0071361
GO:0071456
GO:0071545
GO:0090071
GO:0090394
GO:0097105
GO:0097107
GO:0098542
GO:0098772
GO:0099524
GO:0140013
GO:0140096
GO:0140678
GO:1900425
GO:1902807
GO:1903690
GO:1903860
GO:1904668
GO:1904706
GO:1905450
GO:1990314
GO:1990381
GO:1990782
GO:2000060
GO:2000109
GO:2000134
GO:2000463
GO:2000773
GO:2000808
GO:2001235
ILMN_2517228
ILMN_2594450
U92437_s_at
aa162581_s_at
mMC013699
mMR028908
Participates
as a member of
TP53,MDM2,MDM4,FOXO4,PTEN [nucleoplasm] (Mus musculus)
as an input of
Deubiquitinated PTEN translocates to the cytosol (Mus musculus)
as an output of
USP7 deubiquitinates monoubiquitinated PTEN (Mus musculus)
Other forms of this molecule
Pten [cytosol]
Pten [nucleoplasm]
phospho-Pten [cytosol]
Pten [cytosol]
Pten [nucleoplasm]
Pten [cytosol]
Pten [cytosol]
Pten [cytosol]
Pten [cytosol]
phospho-Pten [cytosol]
phospho-Pten [cytosol]
phospho-Pten [cytosol]
Inferred From
PTEN [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_032986.1
IntEnz
3.1.3.67
,
3.1.3.16
,
3.1.3.48
Ensembl
ENSMUSP00000013807
,
ENSMUSG00000013663
,
ENSMUST00000013807
PRO
O08586
MGI
109583
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9JHL1 NHRF2
0.591
3
UniProt:P62991 UBIQ
0.589
2
UniProt:P02340 Tp53
20
TP53 [cytosol]
(R-MMU-8869337)
PolyUb-TP53 [nucleoplasm]
(R-MMU-6782509)
polySUMO2,3-K386-TP53 [nucleoplasm]
(R-MMU-2997661)
p- S18-Tp53 [nucleoplasm]
(R-MMU-9816424)
phospho-p-S392-TP53 [nucleoplasm]
(R-MMU-9836341)
Me2K-370,382-TP53 [nucleoplasm]
(R-MMU-3222242)
Me2-K373-TP53 [nucleoplasm]
(R-MMU-6805759)
phospho-p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm]
(R-MMU-6804378)
phospho-MeK-370,p-S15,S20-TP53 [nucleoplasm]
(R-MMU-3222226)
phospho-Me-K382,p-S15,S20-TP53 [nucleoplasm]
(R-MMU-3222124)
phospho-Me1-K372,p-S15,S20-TP53 [nucleoplasm]
(R-MMU-6805719)
phospho-Ac-K120,p-S15,S20-TP53 [nucleoplasm]
(R-MMU-6805656)
phospho-Ac-K120,K382,p-S15,S20-TP53 [nucleoplasm]
(R-MMU-6805631)
phospho-Ac-K382,p-S15,S20-TP53 [nucleoplasm]
(R-MMU-5628868)
phospho-p-S15,S392-TP53 [nucleoplasm]
(R-MMU-3222015)
phospho-p-S315-TP53 [nucleoplasm]
(R-MMU-6805106)
phospho-p-S15,S33,S46-TP53 [nucleoplasm]
(R-MMU-6805268)
phospho-p-S15,S20-TP53 [nucleoplasm]
(R-MMU-69683)
phospho-p-S15-TP53 [nucleoplasm]
(R-MMU-69507)
TP53 [nucleoplasm]
(R-MMU-69488)
0.537
4
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