Reactome | Mt3 binds copper

Mt3 binds copper

Stable Identifier

R-MMU-6798571

Type

Reaction [binding]

Species

Mus musculus

Compartment

cytosol

ReviewStatus

5/5

General

SBML | | PDF

SVG | | PPTX | SBGN

Mt3 binds 10 atoms of copper(I). Mt3 exhibits a Cu-thionein character stronger than that of the Mt1 and Mt2 isoforms -also present in the mammalian brain-, and it displays a high capacity to bind Cu+ provided that this occurs in non-oxidative milieux (Artells et al, 2014)

Literature References

PubMed ID	Title	Journal	Year
24479872	In vivo-folded metal-metallothionein 3 complexes reveal the Cu-thionein rather than Zn-thionein character of this brain-specific mammalian metallothionein Atrian, S, Palacios, O, Artells, E, Capdevila, M	FEBS J.	2014