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Stat1 [cytosol]
Stable Identifier
R-MMU-629622
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
STAT1, P42225
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Mus musculus)
Cellular responses to mechanical stimuli (Mus musculus)
Response of endothelial cells to shear stress (Mus musculus)
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Mus musculus)
Phosphorylation of STAT1 on tyrosine-701 is enhanced by p-S172-IKBKE (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Interferon Signaling (Mus musculus)
Antiviral mechanism by IFN-stimulated genes (Mus musculus)
ISG15 antiviral mechanism (Mus musculus)
ISGylation of host proteins (Mus musculus)
ISG15 targets [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
ISGylated host proteins [cytosol] (Mus musculus)
ISG15 targets [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Mus musculus)
ISG15 targets [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
ISGylated host proteins [cytosol] (Mus musculus)
ISG15 targets [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
PKR-mediated signaling (Mus musculus)
STAT1,STAT3 binds PKR (Mus musculus)
STAT1, STAT3 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
STAT1,STAT3:EIF2AK2 [cytosol] (Mus musculus)
STAT1, STAT3 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Signaling by Interleukins (Mus musculus)
Interleukin-12 family signaling (Mus musculus)
Interleukin-27 signaling (Mus musculus)
STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex (Mus musculus)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Mus musculus)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
p-Y701-STAT1 and p-Y705-STAT3 dissociate from IL27:IL27 receptor (Mus musculus)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Interleukin-35 Signalling (Mus musculus)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Mus musculus)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Mus musculus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT4 [plasma membrane] (Mus musculus)
STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Mus musculus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
STAT1 and STAT4 associate with IL12RB2:IL6ST receptor (Mus musculus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT4 [plasma membrane] (Mus musculus)
STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
STAT1 associates with IL6ST:IL6ST (Mus musculus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
STAT1,STAT3 associate with IL27RA:IL12RB2 receptor (Mus musculus)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Interleukin-2 family signaling (Mus musculus)
Interleukin-21 signaling (Mus musculus)
IL21 receptor STAT binding (Mus musculus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3:STAT1,STAT3,STAT4,STAT5 [plasma membrane] (Mus musculus)
STAT1,STAT3,STAT4,STAT5 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
STAT1,STAT3,STAT4,STAT5 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
IL21 receptor STAT phosphorylation (Mus musculus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3:STAT1,STAT3,STAT4,STAT5 [plasma membrane] (Mus musculus)
STAT1,STAT3,STAT4,STAT5 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Interleukin-9 signaling (Mus musculus)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Mus musculus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] (Mus musculus)
STATs [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B (Mus musculus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] (Mus musculus)
STATs [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
STATs [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Interleukin-20 family signaling (Mus musculus)
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Mus musculus)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1,STAT2, STAT3, STAT4, STAT5 [plasma membrane] (Mus musculus)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 (Mus musculus)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1,STAT2, STAT3, STAT4, STAT5 [plasma membrane] (Mus musculus)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Mus musculus)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 [plasma membrane] (Mus musculus)
STAT1, STAT3 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3 (Mus musculus)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 [plasma membrane] (Mus musculus)
STAT1, STAT3 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
STAT1, STAT3 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 [plasma membrane] (Mus musculus)
STAT1, STAT3 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
STAT1, STAT3 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Mus musculus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 [plasma membrane] (Mus musculus)
STAT1, STAT3 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Interleukin-4 and Interleukin-13 signaling (Mus musculus)
STAT1,STAT3,STAT6 bind IL13:IL13R type II (Mus musculus)
IL13-bound tyrosine-phosphorylated IL13 receptor type II with STAT1,STAT3,STAT6 [plasma membrane] (Mus musculus)
STAT1,STAT3,STAT6 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
STAT1,STAT3,STAT6 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
STAT1,STAT3,STAT6 phosphorylation (Mus musculus)
IL13-bound tyrosine-phosphorylated IL13 receptor type II with STAT1,STAT3,STAT6 [plasma membrane] (Mus musculus)
STAT1,STAT3,STAT6 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Interleukin-6 family signaling (Mus musculus)
Interleukin-6 signaling (Mus musculus)
Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Mus musculus)
STAT1, STAT3 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane] (Mus musculus)
STAT1, STAT3 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Mus musculus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane] (Mus musculus)
STAT1, STAT3 [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by PDGF (Mus musculus)
Downstream signal transduction (Mus musculus)
STAT binds to the active receptor (Mus musculus)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Mus musculus)
STAT family members [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
STAT family members [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Signaling by SCF-KIT (Mus musculus)
Phosphorylation of STATs (Mus musculus)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Mus musculus)
STATs [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
Recruitment of STATs (Mus musculus)
STATs [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Mus musculus)
STATs [cytosol] (Mus musculus)
Stat1 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:P42225 Stat1
Gene Names
Stat1
Chain
initiator methionine:, chain:2-749
Reference Genes
UCSC:P42225 Stat1
Participates
as an input of
STAT1 associates with IL6ST:IL6ST (Mus musculus)
STAT1 and STAT4 associate with IL12RB2:IL6ST receptor (Mus musculus)
STAT1,STAT3 associate with IL27RA:IL12RB2 receptor (Mus musculus)
STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex (Mus musculus)
Phosphorylation of STAT1 on tyrosine-701 is enhanced by p-S172-IKBKE (Mus musculus)
as a component of
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] (Mus musculus)
STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Mus musculus)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] (Mus musculus)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] (Mus musculus)
as a member of
STAT1,STAT3,STAT6 [cytosol] (Mus musculus)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Mus musculus)
STAT1,STAT3,STAT4,STAT5 [cytosol] (Mus musculus)
ISG15 targets [cytosol] (Mus musculus)
STAT1, STAT3 [cytosol] (Mus musculus)
STAT family members [cytosol] (Mus musculus)
STATs [cytosol] (Mus musculus)
Other forms of this molecule
phospho-Stat1 [nucleoplasm]
phospho-Stat1 [cytosol]
p-Y-Stat1 [nucleoplasm]
p-Y701-Stat1 [cytosol]
phospho-Stat1 [nucleoplasm]
phospho-Stat1 [cytosol]
phospho-Stat1 [nucleoplasm]
Stat1 [cytosol]
phospho-Stat1 [nucleoplasm]
phospho-Stat1 [cytosol]
Stat1 [cytosol]
Stat1 [nucleoplasm]
Stat1 [cytosol]
phospho-Stat1 [cytosol]
phospho-Stat1 [cytosol]
phospho-Stat1 [nucleoplasm]
Inferred From
STAT1 [cytosol]
(Homo sapiens)
Cross References
ZINC - Substances
STAT1_MOUSE
ZINC target
P42225
PRO
P42225
GlyGen
P42225
MGI
103063
ZINC - Predictions - Purchasable
STAT1_MOUSE
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q64705
1
Usf2 [nucleoplasm]
(R-MMU-9023564)
0.576
3
UniProt:Q61069
2
phospho-Usf1 [nucleoplasm]
(R-MMU-9855887)
Usf1 [nucleoplasm]
(R-MMU-9023562)
0.499
2
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