Reactome | Adora3 [plasma membrane]

Adora3 [plasma membrane]

Stable Identifier

R-MMU-5693919

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

ADORA3, Q61618

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Mus musculus)
        
        ADORA1,3 [plasma membrane] (Mus musculus)
        
        Adora3 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Mus musculus)
        
        ADORA1,3 [plasma membrane] (Mus musculus)
        
        Adora3 [plasma membrane] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Mus musculus)
        
        ADORA1,3 [plasma membrane] (Mus musculus)
        
        Adora3 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Mus musculus)
        
        ADORA1,3 [plasma membrane] (Mus musculus)
        
        Adora3 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Mus musculus)
        
        ADORA1,3 [plasma membrane] (Mus musculus)
        
        Adora3 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Mus musculus)
        
        ADORA1,3 [plasma membrane] (Mus musculus)
        
        Adora3 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Nucleotide-like (purinergic) receptors (Mus musculus)
        
        Adenosine P1 receptors (Mus musculus)
        
        A1 and A3 receptors bind adenosine (Mus musculus)
        
        ADORA1,3 [plasma membrane] (Mus musculus)
        
        Adora3 [plasma membrane] (Mus musculus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Mus musculus)
        
        ADORA1,3 [plasma membrane] (Mus musculus)
        
        Adora3 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q61618

Gene Names

Adora3

Reference Genes

ENSEMBL:ENSMUSG00000000562

Participates

as a member of

ADORA1,3 [plasma membrane] (Mus musculus)

Inferred From

ADORA3 [plasma membrane] (Homo sapiens)

Cross References

ZINC - Investigational

AA3R_MOUSE

ZINC - Substances

AA3R_MOUSE

ZINC target

Q61618

PRO

Q61618

MGI

104847

ZINC - Predictions - Purchasable

AA3R_MOUSE

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