Reactome | Trappc2 [cytosol]

Trappc2 [cytosol]

Stable Identifier

R-MMU-5683757

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

TRAPPC2, Q9CQP2

Locations in the PathwayBrowser

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Metabolism of proteins (Mus musculus)

- Post-translational protein modification (Mus musculus)
  - Asparagine N-linked glycosylation (Mus musculus)
    - Transport to the Golgi and subsequent modification (Mus musculus)
      - ER to Golgi Anterograde Transport (Mus musculus)
        
        COPII-mediated vesicle transport (Mus musculus)
        
        COPII coat binds TRAPPCII and RAB1:GDP (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
        
        CSNK1D phosphorylates SEC23 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
        
        Nucleotide exchange on RAB1 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)

Vesicle-mediated transport (Mus musculus)

- Membrane Trafficking (Mus musculus)
  - ER to Golgi Anterograde Transport (Mus musculus)
    - COPII-mediated vesicle transport (Mus musculus)
      - COPII coat binds TRAPPCII and RAB1:GDP (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
      - CSNK1D phosphorylates SEC23 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
      - Nucleotide exchange on RAB1 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
  - Rab regulation of trafficking (Mus musculus)
    - RAB GEFs exchange GTP for GDP on RABs (Mus musculus)
      - TRAPPC complexes exchange GTP for GDP on RAB1 (Mus musculus)
        
        TRAPPCs [cytosol] (Mus musculus)
        
        TRAPPCII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)
        
        TRAPPCIII [cytosol] (Mus musculus)
        
        Trappc2 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9CQP2

Gene Names

Trappc2

Reference Genes

BioGPS Gene:66050 Trappc2

BioGPS Gene:66226 Trappc2

ENSEMBL:ENSMUSG00000079317

ENSEMBL:ENSMUSG00000079317.11 Trappc2

KEGG Gene (Mus musculus):66050 Trappc2

KEGG Gene (Mus musculus):66226 Trappc2

Monarch:66050 Trappc2

Monarch:66226 Trappc2

NCBI Gene:66050 Trappc2

NCBI Gene:66226 Trappc2

UCSC:Q9CQP2 Trappc2

Reference Transcript

Other Identifiers

10518167

10603166

1432158_a_at

162867_r_at

17539626

4386742

4543395

4829882

4845784

4856693

4941372

4992959

5155352

5197522

5290246

5551042

66226

A_51_P102631

A_55_P1969344

A_55_P2186205

GO:0001222

GO:0001501

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005768

GO:0005783

GO:0005793

GO:0005794

GO:0006888

GO:0006901

GO:0010628

GO:0016192

GO:0030008

GO:0031410

GO:0043226

GO:0043231

GO:0044325

GO:0048208

GO:0048471

GO:0048856

GO:0061024

GO:0065003

GO:0099022

GO:1990071

GO:1990072

ILMN_1235440

ILMN_2438032

ILMN_2506855

mMC020215

mMR027549

Participates

as a component of

Inferred From

TRAPPC2 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_079595.1, XP_006533982.1, NP_001300651.1, XP_006533980.1, NP_079708.2, XP_006533981.1

Ensembl

ENSMUST00000116495, ENSMUSP00000112195, ENSMUST00000112194, ENSMUSP00000107813, ENSMUSG00000079317

PRO

Q9CQP2

MGI

1913476

PDB

1H3Q, 2J3W

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