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RAF/MAPK scaffolds [cytosol]
Stable Identifier
R-MMU-5672717
Type
Set [CandidateSet]
Species
Mus musculus
Compartment
cytosol
,
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK1/MAPK3 signaling (Mus musculus)
RAF/MAP kinase cascade (Mus musculus)
MAP2K and MAPK activation (Mus musculus)
Dissociation of RAS:RAF complex (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
Dual mechanism MAPK inhibitors bind MAPKs (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
MAP2Ks and MAPKs bind to the activated RAF complex (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
MAP2Ks phosphorylate MAPKs (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
RAF phosphorylates MAP2K dimer (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Mus musculus)
RAF/MAPK scaffolds [cytosol] (Mus musculus)
Participants
members
p-S311 KSR1:MARK3 [cytosol]
(Mus musculus)
candidates
KSR2 [cytosol]
(Mus musculus)
Iqgap1 [cytosol]
(Mus musculus)
Cnksr1 [cytosol]
(Mus musculus)
Cnksr2 [cytosol]
(Mus musculus)
Arrb1 [cytosol]
(Mus musculus)
Arrb2 [cytosol]
(Mus musculus)
Focal Adhesion/Focal contacts [plasma membrane]
(Mus musculus)
Participates
as an output of
Dissociation of RAS:RAF complex (Mus musculus)
as an input of
MAP2Ks and MAPKs bind to the activated RAF complex (Mus musculus)
as a component of
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Mus musculus)
Inferred From
RAF/MAPK scaffolds [cytosol]
(Homo sapiens)
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