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PAR-PARP2 [nucleoplasm]
Stable Identifier
R-MMU-5651715
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
O88554
Locations in the PathwayBrowser
Expand all
DNA Repair (Mus musculus)
Base Excision Repair (Mus musculus)
Resolution of Abasic Sites (AP sites) (Mus musculus)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Mus musculus)
POLB-Dependent Long Patch Base Excision Repair (Mus musculus)
PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
PARG dePARylates PARP1,PARP2 (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Mus musculus)
PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
DNA Double-Strand Break Repair (Mus musculus)
Homology Directed Repair (Mus musculus)
HDR through MMEJ (alt-NHEJ) (Mus musculus)
PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
Nucleotide Excision Repair (Mus musculus)
Global Genome Nucleotide Excision Repair (GG-NER) (Mus musculus)
DNA Damage Recognition in GG-NER (Mus musculus)
PARP1 or PARP2 PARylates DDB2 and autoPARylates (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
Dual Incision in GG-NER (Mus musculus)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Mus musculus)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Mus musculus)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Mus musculus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Mus musculus)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
Formation of Incision Complex in GG-NER (Mus musculus)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Mus musculus)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Mus musculus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
CHD1L is recruited to GG-NER site (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
Formation of the pre-incision complex in GG-NER (Mus musculus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
RNF111 ubiquitinates SUMOylated XPC (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
Recruitment of XPA and release of CAK (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
SUMOylation of XPC (Mus musculus)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
TFIIH binds GG-NER site to form a verification complex (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Mus musculus)
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
PAR-PARP2 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:O88554
Reference Genes
BioGPS Gene:11546
ENSEMBL:ENSMUSG00000036023
ENSEMBL:ENSMUSG00000036023.7
KEGG Gene (Mus musculus):11546
Monarch:11546
NCBI Gene:11546
UCSC:O88554
Reference Transcript
RefSeq:XM_006518442.3
RefSeq:NM_009632.2
Other Identifiers
100903_at
10414497
11546
1417800_at
17299518
4336300
4370706
4463012
4479624
4637576
4851931
4875279
5095908
5127596
5189363
5227675
5257386
5273858
5309083
5362810
5367829
5442729
5532117
A_51_P471630
A_52_P227445
A_55_P2735280
GE35037
GO:0003012
GO:0003677
GO:0003682
GO:0003684
GO:0003824
GO:0003950
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0006281
GO:0006284
GO:0006302
GO:0006325
GO:0006974
GO:0008152
GO:0012501
GO:0016740
GO:0016757
GO:0016779
GO:0022414
GO:0023052
GO:0030154
GO:0030592
GO:0031491
GO:0036211
GO:0043226
GO:0046697
GO:0048856
GO:0061051
GO:0070212
GO:0070213
GO:0072572
GO:0090649
GO:0090734
GO:0097191
GO:0110088
GO:0140096
GO:0140294
GO:0140805
GO:0140806
GO:0140807
GO:0140861
GO:0160004
GO:1990404
ILMN_1226731
ILMN_2598576
aa638884_s_at
mMC007948
Participates
as a candidate of
PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Other forms of this molecule
PARP2 [nucleoplasm]
Inferred From
PAR-PARP2 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
L-glutamyl-5-poly(ADP-ribose) at unknown position
PsiMod Name
L-glutamyl-5-poly(ADP-ribose)
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-glutamyl-5-poly(ADP-ribose).
Cross References
RefSeq
NP_033762.1
,
XP_006518505.1
ZINC - Substances
PARP2_MOUSE
ZINC target
O88554
Ensembl
ENSMUSP00000048877
,
ENSMUSG00000036023
,
ENSMUST00000036126
PRO
O88554
ZINC - Predictions - Purchasable
PARP2_MOUSE
MGI
1341112
PDB
1GS0
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