Reactome | Iqcb1 [cytosol]

Iqcb1 [cytosol]

Stable Identifier

R-MMU-5626648

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

IQCB1, Q8BP00

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Mus musculus)

- Cilium Assembly (Mus musculus)
  - Anchoring of the basal body to the plasma membrane (Mus musculus)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Iqcb1 [cytosol] (Mus musculus)
      - mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Iqcb1 [cytosol] (Mus musculus)
    - C2CD3 binds the mother centriole (Mus musculus)
      - mother centriole [cytosol] (Mus musculus)
        
        Iqcb1 [cytosol] (Mus musculus)
      - mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Iqcb1 [cytosol] (Mus musculus)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Mus musculus)
      - basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        Iqcb1 [cytosol] (Mus musculus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
        
        basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        Iqcb1 [cytosol] (Mus musculus)
    - CP110 and CEP97 dissociate from the centriole (Mus musculus)
      - basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        Iqcb1 [cytosol] (Mus musculus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Iqcb1 [cytosol] (Mus musculus)
    - MARK4 binds ODF2 in the centriole (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Iqcb1 [cytosol] (Mus musculus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Iqcb1 [cytosol] (Mus musculus)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Mus musculus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
        
        basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        Iqcb1 [cytosol] (Mus musculus)
    - Recruitment of transition zone proteins (Mus musculus)
      - basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        Iqcb1 [cytosol] (Mus musculus)
      - basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        Iqcb1 [cytosol] (Mus musculus)
    - The distal appendage proteins recruit TTBK2 (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Iqcb1 [cytosol] (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Iqcb1 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q8BP00

Gene Names

Iqcb1

Reference Genes

BioGPS Gene:320299 Iqcb1

ENSEMBL:ENSMUSG00000022837

ENSEMBL:ENSMUSG00000022837.15 Iqcb1

KEGG Gene (Mus musculus):320299 Iqcb1

Monarch:320299 Iqcb1

NCBI Gene:320299 Iqcb1

UCSC:Q8BP00 Iqcb1

Reference Transcript

Other Identifiers

10435525

113279_at

1434770_at

17325386

320299

4305805

4509905

4541274

4634728

4664157

4842789

4876114

5018135

5026782

5042727

5045498

5071065

5141682

5188040

5192360

5228875

5240772

5264553

5307528

5366633

5390815

5494499

5556938

5563896

A_51_P307567

A_66_P132077

GE1531021

GO:0001750

GO:0005515

GO:0005516

GO:0005634

GO:0005654

GO:0005737

GO:0005813

GO:0005815

GO:0005856

GO:0005929

GO:0015630

GO:0019899

GO:0030030

GO:0030154

GO:0032391

GO:0043226

GO:0044782

GO:0045171

GO:0045494

GO:0048496

GO:0048856

GO:0060271

GO:0072686

ILMN_1252447

ILMN_2635348

mMC010800

Participates

as a component of

Inferred From

IQCB1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_006522312.1, XP_006522311.1, XP_006522310.1, NP_796102.2

Ensembl

ENSMUST00000114819, ENSMUST00000023535, ENSMUSP00000023535, ENSMUSP00000110467, ENSMUSG00000022837

PRO

Q8BP00

MGI

2443764

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